ArticleAmerican journal of physiology. Renal physiology2026
The response to kidney injury is epigenetically regulated through the activation of bivalent genes.
Article in American journal of physiology. Renal physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Epigenetic regulation through histone modifications plays a crucial role in driving cellular state transitions. Regulating gene transcription through bivalency, the co-occurrence of activating histone H3 lysine 4 trimethylation (H3K4me3) and repressive histone H3 lysine 27 trimethylation (H3K27me3) histone marks, drives cell fate in development; however, its role in kidney injury is not known. Here, we investigated bivalent gene activation in the adult male
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