Evidence map›Paper›PMID 41500304›Full record

ArticleEnvironmental research2026

Association between noise pollution exposure and incident breast cancer in the Sister Study.

Brittney A Gedeon, Che-Jung Chang, Peter James, Rena R Jones, Alexandra J White

Abstract read
In one paragraph

Article in Environmental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brittney A GedeonDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Che-Jung ChangEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Peter JamesCenter for Occupational and Environmental Health, University of California Davis, Davis, CA, USA; Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA; Department of Population Medicine and Harvard Pilgrim Health Care Institute, Harvard Medical School, Boston, MA, USA.
Rena R JonesOccupational & Environmental Epidemiology Branch, Division of Cancer Epidemiology & Genetics, National Cancer Institute, Rockville, MD, USA.
Alexandra J WhiteEpidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA. Electronic address: alexandra.white@nih.gov.

Funding

Environment and Cancer EpidemiologyZIAES103332 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WHITE, ALEXANDRA · 2019 to 2025
$8.9M
Cancer Care Quality Training ProgramT32CA116339 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ETHAN M. BASCH, Stephanie Brooke Wheeler · 2018 to 2026
$3.0M
Genetic and Environmental Risk Factors for Breast Cancer: The Sister StudyZ01ES044005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 1999 to 2008
$1.3M
Intramural NIH HHS Z01 ES044005Intramural NIH HHS Z99 ES999999Intramural NIH HHS ZIA ES103332NCI NIH HHS T32 CA116339
6 · The paper itself

Abstract

Noise exposure may contribute to cancer risk via disrupting sleep patterns and the autonomic nervous system. While modest positive associations between noise exposure and breast cancer incidence were observed in Europe, no study has been done in the United States. We examined the association between noise exposure and incident breast cancer in a large nationwide prospective cohort of women in the U.S. We included 46,809 participants in the Sister Study (ages 35-74, enrolled 2003-2009). Median daytime and nighttime anthropogenic noise at the participants' baseline residence was estimated using a U.S. National Park Service noise model. Cox proportional hazards models estimated hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between incident breast cancer and exposure to noise by quartiles and per 10 dB increase, adjusted for sociodemographic and urbanicity-related factors and stratifying by estrogen receptor (ER) status. During an average of 12.5 years of follow-up, 4,271 breast cancer cases were diagnosed. Higher daytime noise exposure was associated with higher breast cancer incidence (HR

Indexed as

Breast NeoplasmsEnvironmental ExposureNoiseAdultAgedFemaleHumansIncidenceMiddle AgedProportional Hazards ModelsProspective StudiesUnited States

Identifiers

PMID41500304
PMCPMC12914653

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.