Evidence map›Paper›PMID 41499802›Full record

ArticleClinical endoscopy2026

Prognosis of Korean patients with familial adenomatous polyposis who did not undergo colectomy: a retrospective study.

Min Kwan Kwon, Jin Hee Noh, Ji Yong Ahn, Woochang Lee, Seok-Byung Lim, Yong Sang Hong, Seung Wook Hong, Sung Wook Hwang, Sang Hyoung Park, Byong Duk Ye and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Min Kwan KwonDepartment of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Jin Hee NohGastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Ji Yong AhnGastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Woochang LeeLaboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Seok-Byung LimSurgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Yong Sang HongOncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Seung Wook HongGastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Sung Wook HwangGastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Sang Hyoung ParkGastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Byong Duk YeGastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Jeong-Sik ByeonGastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Seung-Jae MyungGastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Suk-Kyun YangGastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Dong-Hoon YangGastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Funding

Ministry of Education 2021R1A6A1A03040260National Research Foundation of Korea
6 · The paper itself

Abstract

backgroundThe International Society for Gastrointestinal Hereditary Tumors polyposis scoring system (IPSS) categorizes familial adenomatous polyposis (FAP) according to the burden of colorectal polyps and histology. However, the prognosis of patients with uncolectomized FAP has not been established.

methodsMedical records of patients diagnosed with FAP between 1991 and 2021 were reviewed, and the IPSS stage was determined. The cumulative upstaging rate and risk factors for IPSS upstaging during surveillance were analyzed in patients without colectomies.

resultsAmong 237 patients, 35 (28.9%) with IPSS stages 0-2 did not undergo colectomy. The cumulative risk of upstaging was 0%, 31%, 54%, and 73% at 1, 3, 7, and 10 years after FAP diagnosis, respectively. In univariate analysis, age (hazard ratio [HR], 1.05; 95% confidence interval [CI], 1.01-1.08; p=0.014) and having an ampulla of Vater adenoma (HR, 3.95; 95% CI, 1.17-13.30; p=0.027) were associated with upstaging. Multivariate analysis revealed that each 1-year increase in age was an independent risk factor of upstaging (adjusted HR, 1.04; 95% CI, 1.01-1.09; p=0.027).

conclusionsIn our analysis, patients with uncolectomized FAP and IPSS stages 0-2 at diagnosis showed a time-dependent progression in the IPSS stage.

Indexed as

AdenomaAdenomatous polyposis coliAmpulla of vaterColorectumSurveillance

Identifiers

PMID41499802
PMCPMC13054502

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