Trial reportPloS one2026
Impact of exercise sequence in concurrent training on insulin resistance, glycemic control, and blood pressure in Type 2 diabetes.
Trial report in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Exercise and physical activity interventions in type 2 diabetes mellitus.Frontiers in endocrinology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study compared the effects of aerobic followed by resistance (CART) and resistance followed by aerobic (CRAT) training on insulin sensitivity, glycemic control, and blood pressure against a non-exercising control group (COT). 39 patients with type 2 diabetes were randomly assigned to CART (n = 13), CRAT (n = 13), or COT (n = 13) for a 12-week supervised program. Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) improved significantly (F = 24.460, p = 0.001, η² = 0.62), with CRAT showing a modestly greater reduction than CART (MD = 0.303, p = 0.022), while both training sequences produced greater improvements compared to COT (CART: MD = -0.493, p = 0.001; CRAT: MD = -0.796, p = 0.001). Fasting Blood Sugar (FBS) decreased significantly (F = 16.206, p = 0.001, η² = 0.519) in both CART (MD = -10.747, p = 0.001) and CRAT (MD = -11.459, p = 0.001) relative to COT, though no difference emerged between the two exercise sequences (MD = 0.712, NS). Systolic Blood Pressure (SBP) also declined in CART (MD = -4.896, p = 0.005) and CRAT (MD = -5.681, p = 0.001) compared with COT (F = 8.968, p = 0.001, η² = 0.374), again without a significant sequence effect (MD = 0.785, NS). No significant between-group changes were observed in Diastolic Blood Pressure (DBP). Overall, concurrent training effectively reduced insulin resistance, improved glycemic control, and lowered SBP in patients with type 2 diabetes. While CRAT offered a modest additional benefit for HOMA-IR, the findings suggest that concurrent training, regardless of sequence, provides meaningful clinical benefits for managing type 2 diabetes. Trial registrationPan African Clinical Trials Registry (PACTR202509591505325) pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=37070.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.