Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
21 authors.
Ruoci HuDepartment of Physiology and Biophysics, College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0001-6387-5611
Jooman ParkDepartment of Physiology and Biophysics, College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0001-5368-5769
Yanyu QianDepartment of Physiology and Biophysics, College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.
Shaolei XiongDepartment of Physiology and Biophysics, College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0003-3111-891X
Ahmad Hamza ElsabbaghDepartment of Physiology and Biophysics, College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0009-0009-2012-4012
Aditya ChhikaraDepartment of Physiology and Biophysics, College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0009-0004-9481-5020
Huailing FanDepartment of Physiology and Biophysics, College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.
Zuoxiao ShiDepartment of Physiology and Biophysics, College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.
Lifeng LiuDepartment of Physiology and Biophysics, College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.
Yanhui LiDepartment of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL 60612, USA.
Zhenyuan SongDepartment of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0001-8750-5762
Abeer M MahmoudDivision of Endocrinology, Department of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0002-0295-6706
Jiwang ChenDivision of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0009-0001-3061-4383
Joseph A BaurDepartment of Physiology and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-8262-6549
Yanlin HePennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA 70808, USA.ORCID 0000-0002-5471-9016
Brian T LaydenDivision of Endocrinology, Department of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.
Zhenqi ZhouDivision of Endocrinology, Diabetes, and Hypertension, Department of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0001-6560-9704
Pingwen XuDivision of Endocrinology, Department of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0001-9363-4114
Sang-Ging OngDepartment of Pharmacology and Regenerative Medicine, College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0003-0182-8769
Zilai WangDepartment of Microbiology and Immunology, University of Illinois Chicago, Chicago, IL 60612, USA.
Yuwei JiangDepartment of Physiology and Biophysics, College of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0002-5082-8012
Funding
Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI RICHARD D MINSHALL · 2017 to 2026
$13.6M
Regulation of beige adipocyte maintenance and its impact on metabolic outcomesR01DK132398 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Yuwei Jiang · 2022 to 2026
$2.6M
Molecular regulation of adipose tissue development, homeostasis and expansionK01DK111771 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI JIANG, YUWEI · 2016 to 2021
$705k
Regulation of adipose lineage plasticity in obesityR03DK127149 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI JIANG, YUWEI · 2021 to 2022
Beige adipocytes are inducible thermogenic fat cells that emerge within white adipose tissue (WAT) in response to thermogenic stimuli and confer metabolic benefits. However, obesity impairs the generation of beige adipocytes, and the underlying mechanisms remain poorly understood. Here, we show that obesity leads to a loss of adipose progenitor cells (APCs) in WAT, accompanied by reduced estrogen (E2) levels and nicotinamide phosphoribosyltransferase (NAMPT) expression. Supplementation with E2 or nicotinamide mononucleotide (NMN), an NAMPT-derived nicotinamide adenine dinucleotide (NAD
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
ERα activates NAMPT/IL-33 signaling to enhance beige thermogenesis and metabolic fitness. · full record | OpenQuestion