Evidence map›Paper›PMID 41499393›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution.

Nina Vittorelli, Cintia Gómez-Muñoz, Irina Andriushchenko, Louis Ollivier, Nicolas Agier, Stéphane Delmas, Yann Corbeau, Guillaume Achaz, Marco Cosentino Lagomarsino, Gianni Liti and 2 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nina VittorelliSorbonne Université, CNRS, Computational, Quantitative and Synthetic Biology, CQSB, Paris F-75005, France.ORCID 0009-0007-7359-6625
Cintia Gómez-MuñozSorbonne Université, CNRS, Computational, Quantitative and Synthetic Biology, CQSB, Paris F-75005, France.ORCID 0000-0003-2820-9810
Irina AndriushchenkoSorbonne Université, CNRS, Computational, Quantitative and Synthetic Biology, CQSB, Paris F-75005, France.ORCID 0009-0003-7392-3842
Louis OllivierSorbonne Université, CNRS, Computational, Quantitative and Synthetic Biology, CQSB, Paris F-75005, France.
Nicolas AgierSorbonne Université, CNRS, Computational, Quantitative and Synthetic Biology, CQSB, Paris F-75005, France.
Stéphane DelmasSorbonne Université, CNRS, Computational, Quantitative and Synthetic Biology, CQSB, Paris F-75005, France.ORCID 0000-0001-5523-7548
Yann CorbeauSorbonne Université, CNRS, Computational, Quantitative and Synthetic Biology, CQSB, Paris F-75005, France.
Guillaume AchazCentre Interdisciplinaire de Recherche en Biologie, Collège de France, Université PSL, CNRS, INSERM, Paris F-75005, France.ORCID 0000-0003-4514-5935
Marco Cosentino LagomarsinoIFOM- Istituto Fondazione di Oncologia Molecolare, Milan 20139, Italy.ORCID 0000-0003-0235-0445
Gianni LitiUniversité Côte d'Azur, CNRS, INSERM, IRCAN, 06107 Nice Cedex 2, France.
Bertrand LlorenteCRCM, Aix Marseille Université, CNRS, INSERM, Institut Paoli Calmettes, 13273 Marseille Cedex 09, France.ORCID 0000-0002-6291-5797
Gilles FischerSorbonne Université, CNRS, Computational, Quantitative and Synthetic Biology, CQSB, Paris F-75005, France.ORCID 0000-0001-5732-2682

Funding

Agence Nationale de la Recherche (ANR) ANR-20-CE12-0020
6 · The paper itself

Abstract

Evolutionary transitions in mating strategy have profound consequences for genetic variation and adaptation. In

Indexed as

Biological EvolutionEvolution, MolecularGenes, Mating Type, FungalPolyploidySaccharomyces cerevisiaeDeoxyribonucleases, Type II Site-SpecificGenome, FungalHeterozygoteMutationSaccharomyces cerevisiae ProteinsDeoxyribonucleases, Type II Site-SpecificHO protein, S cerevisiaeSaccharomyces cerevisiae Proteinsheterothallismmatingmating-type switchingyeast

Identifiers

PMID41499393
PMCPMC12799175

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.