Evidence map›Paper›PMID 41499244›Full record

Trial reportPsycho-oncology2026

Interrelationship Between Patient and Family Caregiver Outcomes Following Lung Cancer Surgery: A Secondary Analysis of a Randomized Controlled Trial.

Mandisa L Keswa, Oluwatimilehin Okunowo, Joycelynne Palmer, Dan Raz, Loretta Erhunmwunsee, Betty Ferrell, Jae Y Kim, Virginia Sun

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psycho-oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mandisa L KeswaKaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California, USA.ORCID https://orcid.org/0009-0003-2270-915X
Oluwatimilehin OkunowoDivision of Biostatistics, Department of Computational and Quantitative Medicine, City of Hope, Duarte, California, USA.
Joycelynne PalmerDivision of Biostatistics, Department of Computational and Quantitative Medicine, City of Hope, Duarte, California, USA.
Dan RazDivision of Thoracic Surgery, Department of Surgery, City of Hope, Duarte, California, USA.
Loretta ErhunmwunseeDivision of Thoracic Surgery, Department of Surgery, City of Hope, Duarte, California, USA.
Betty FerrellDepartment of Population Sciences, City of Hope, Duarte, California, USA.ORCID https://orcid.org/0000-0003-0061-5235
Jae Y KimDivision of Thoracic Surgery, Department of Surgery, City of Hope, Duarte, California, USA.ORCID https://orcid.org/0000-0003-3905-5976
Virginia SunDepartment of Population Sciences, City of Hope, Duarte, California, USA.

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI John Charles Williams · 1985 to 2026
$86.3M
The Impact of Social Determinants of Health Domains on Lung Cancer Surgery Family Caregivers and PatientsR01CA217841 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI KIM, JAE, SUN, VIRGINIA CHIH-YI · 2018 to 2022
$3.9M
NCI NIH HHS P30 CA033572NCI NIH HHS P30CA033572NCI NIH HHS R01 CA217841NIH HHS R01CA217841
6 · The paper itself

Abstract

introductionWhile surgery is considered a standard treatment for patients diagnosed with early-stage lung cancer, it often brings significant challenges for patients including functional limitations and post-operative symptoms. Family caregivers play a critical role in care coordination, post-operative management, and addressing emotional distress often with limited preparation and support. Despite their importance, few studies have assessed the interrelationship between patient and caregiver outcomes during the peri-operative period.

methodsThis study is a secondary analysis of data from a randomized controlled trial involving 190 patient-caregiver dyads who participated in a dyadic multimedia self-management intervention. Structural equation modeling (SEM) was used to evaluate the impact of various sociodemographic variables and psychosocial mediators on dyadic outcomes.

resultsSelf-efficacy was a consistent predictor, with positive effects on preparedness and quality of life (QOL) and negative effects on psychological distress. While activation and knowledge were positively associated with self-efficacy and preparedness, they showed minimal effects on caregiver burden and distress. When evaluating the interdependent relationship, higher patient QOL was associated with improved caregiver preparedness and reduced burden. Caregiver distress significantly predicted greater patient distress and lower patient QOL.

conclusionsThe results of this study support the interdependent, bi-directional associations of patient and caregiver well-being. Further multi-media interventions in the peri-operative period focused on self-efficacy and promoting emotional resilience among caregivers may substantially improve post-operative outcomes for both members of the dyad.

Indexed as

CaregiversLung NeoplasmsPsychological DistressQuality of LifeSelf EfficacyAdaptation, PsychologicalAdultAgedFemaleHumansMaleMiddle AgedSelf-ManagementStress, Psychologicaldyadic outcomesfamily caregiverslung cancer surgerypsychological distressquality of lifeself‐efficacystructural equation modeling

Identifiers

PMID41499244
PMCPMC13625620

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.