Evidence map›Paper›PMID 41499229›Full record

ArticleJournal of synchrotron radiation2026

50th anniversary of the Stanford SSRL synchrotron radiation and protein crystallography initiative.

John R Helliwell, Colin Nave, D Marian Szebenyi

Abstract readHistorical Article
In one paragraph

Article in Journal of synchrotron radiation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

John R HelliwellDepartment of Chemistry, University of Manchester, Manchester M13 9PL, United Kingdom.ORCID 0000-0002-0520-7540
Colin NaveDiamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, United Kingdom.ORCID 0000-0002-8340-8380
D Marian SzebenyiMacCHESS, CHESS, Cornell University, Ithaca, USA.ORCID 0000-0003-0229-9985

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We provide a historical introduction spanning the past 50 years of synchrotron radiation protein crystallography. We then provide a resume of current trends. These help us to celebrate the huge influence that synchrotron radiation, and now X-ray lasers, has had on the scope of protein crystallography. It has also accelerated the development of closely allied methods such as neutron protein crystallography, which has adopted the synchrotron Laue method as its own as well as developing monochromatic and time-of-flight methods. Also, the democratic access to central synchrotron facility beamlines has prompted similarly operated centres of electron cryo-microscopy and micro-electron diffraction. We offer our thoughts on the current trends across this scientific landscape.

Indexed as

ProteinsSynchrotronsCrystallographyCrystallography, X-RayHistory, 20th CenturyHistory, 21st CenturyProteinsmacromolecular crystallographyprotein crystallographySSRL Stanfordstructural biologysynchrotron radiationXFELs

Identifiers

PMID41499229
PMCPMC12809441

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.