Evidence map›Paper›PMID 41499158›Full record

Trial reportNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2026

Tailoring e-Cigarette Health Messages by Vaping Status: How Source and Message Presentation Type Shape Young Adults' Perceptions.

Donghee Nicole Lee, Andrea C Villanti, Elise M Stevens

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Donghee Nicole LeePopulation Sciences in the Pacific Program, University of Hawaii Cancer Center, Honolulu, HI, USA.ORCID 0000-0002-9932-4376
Andrea C VillantiDepartment of Health Behavior, Society & Policy, Rutgers School of Public Health, Piscataway, NJ, USA.ORCID 0000-0003-3104-966X
Elise M StevensDepartment of Population and Quantitative Health Sciences, Division of Preventive and Behavioral Medicine, UMass Chan Medical School, Worcester, MA, USA.ORCID 0000-0002-0494-4362

Funding

Impact of Nicotine Messaging on Nicotine Beliefs and Tobacco Use BehaviorR01DA051001 · NIDA · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI STRASSER, ANDREW A, VILLANTI, ANDREA · 2020 to 2022
$1.4M
Young Adults Responses to E-Cigarette Advertisement Features and the Effects of Restricting Features on Tobacco UseR00DA046563 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI STEVENS, ELISE MARIE · 2021 to 2023
$914k
Identifying and examining the effects of source and presentation on responses to electronic cigarette public education messages in young adult vapers and non-vapersK99CA281094 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LEE, DONGHEE NICOLE · 2024 to 2025
$289k
FDA Center for Tobacco Products (CTP) K99CA281094National Institute on Drug Abuse of the National Institutes of Health (NIH) R00DA046563National Institute on Drug Abuse of the National Institutes of Health (NIH) R01DA051001NCI NIH HHS K99 CA281094NIDA NIH HHS R00 DA046563NIDA NIH HHS R01 DA051001
6 · The paper itself

Abstract

introductionThis study examined how message sidedness (one-sided vs. two-sided) and source (expert vs. peer) influence young adults' perceptions of e-cigarette heath messages, with attention to differences between those who currently vape, those who ever vaped and never vaped.

methodsWe conducted a 2 (sidedness) x 2 (source) online experiment with a sample of young adults (n = 802, Mage = 21.49). Participants were randomly assigned to view 18 messages about the health effects of vaping. After each message, they rated message and source perceptions. Following exposure to all messages, they completed measures assessing e-cigarette attitudes, risk beliefs, behavioral intentions, and demographics. Generalized linear models were used to examine the effects of message conditions and vaping status on outcomes, adjusting for demographics.

resultsParticipants reported higher trust in experts than peers (p<.001) and more positive message perceptions from expert-delivered messages (p=.048). One-sided messages elicited greater perceived threat to freedom (p<.001) and more positive e-cigarette attitudes than two-sided messages (p=.037) among those who currently vape. Two-sided messages elicited greater anger than one-sided messages among those who ever vaped (p=.041). Participants who never vaped, ever vaped, and currently vape reported the highest trust in the FDA (ps < 0.001) and the lowest trust in influencers (ps < 0.001).

conclusionsTailoring message design to audience's vaping status can strengthen e-cigarette health messages. Expert sources may be more effective in prevention campaigns, while two-sided messages may enhance cessation efforts. Results show that message source and sidedness interact with vaping status to meaningfully shape message perceptions. IMPLICATIONS: This study highlights the importance of tailoring e-cigarette health messages to young adults' vaping status. Health experts (ie, FDA and medical school researchers) are viewed as more credible than peers, underscoring their value as message sources. Additionally, message sidedness plays a critical role: compared to one-sided messages, two-sided messages that acknowledge reasons for vaping resonate more with those who currently vape, while one-sided messages that only present information resonate more with those who ever vaped. These insights can guide the design of targeted public health campaigns, informing both vaping prevention strategies for those not vaping and cessation efforts for those currently vaping, ultimately enhancing campaign effectiveness across diverse young adult populations.

Indexed as

Electronic Nicotine Delivery SystemsHealth PromotionVapingAdolescentAdultFemaleHumansMaleMedia ExposurePerceptionYoung Adult

Identifiers

PMID41499158
PMCPMC13098767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.