Evidence map›Paper›PMID 41499147›Full record

ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2026

Incidence and prevalence of kidney replacement therapy in Central and Eastern Europe-trends from the ERA Registry.

Marjolein Bonthuis, Anneke Kramer, Sevcan A Bakkaloğlu, Jaakko Helve, Nikola Gjorgjievski, Halima Resic, Anders Åsberg, Nicos Mitsides, Alicja M Dębska-Ślizień, Kirill S Komissarov and 16 more

Abstract read
In one paragraph

Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Marjolein BonthuisERA Registry, Amsterdam UMC location University of Amsterdam, Medical Informatics, Amsterdam, The Netherlands.ORCID 0000-0003-1719-940X
Anneke KramerERA Registry, Amsterdam UMC location University of Amsterdam, Medical Informatics, Amsterdam, The Netherlands.ORCID 0000-0002-7560-2669
Sevcan A BakkaloğluGazi University, Faculty of Medicine, Department of Pediatric Nephrology, Ankara, Türkiye.
Jaakko HelveFinnish Registry for Kidney Diseases, Finnish Institute for Health and Welfare, Helsinki, Finland.
Nikola GjorgjievskiUniversity Clinic of Nephrology, Skopje, North Macedonia.
Halima ResicSociety of Nephrology and Dialysis of Bosnia and Herzegovina, Sarajevo, Bosnia and Herzegovina.
Anders ÅsbergDepartment of Transplantation Medicine, Oslo University Hospital - Rikshospitalet, Oslo, Norway.
Nicos MitsidesCyprus Renal Registry, Health Monitoring Unit, Ministry of Health, Nicosia, Cyprus.
Alicja M Dębska-ŚlizieńMedical University of Gdańsk, Department of Nephrology, Transplantology and Internal Diseases, Gdańsk, Poland.
Kirill S KomissarovState Institution "Minsk Scientific and Practical Center for Surgery, Transplantology and Hematology", Minsk, Belarus.
Viktorija KuzemaDepartment of Nephrology, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Nurhan SeyahiIstanbul Üniversity-Cerrahpasa, Cerrahpasa Medical Faculty, Istanbul, Türkiye.ORCID 0000-0001-7427-618X
Belén PonteDepartment of Medicine, Division of Nephology and Hypertension, Geneva University Hospitals, Geneva, Switzerland.
Edita ZiginskieneNephrology Department, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Mirjana LausevicMedical Faculty, University of Belgrade, Nephrology Clinic, University clinical center of Serbia, Belgrade, Serbia.
Ivan RychlíkDepartment Internal Medicine, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague, Czechia.
Mai Ots-RosenbergDepartment of Internal Medicine, Tartu University Hospital, Tartu, Estonia.
Evgueniy VazelovDepartment of Internal Diseases, University "Prof. Dr Asen Zlatarov", Burgas, Bulgaria.
George MoustakasNephrology Department, General Hospital of Athens "G. Gennimatas", Athens, Greece.
Adrián OkšaSlovak Medical University, Faculty of Medicine, Bratislava, Slovakia.
Ariana StrakoshaService of Nephrology, UHC "Mother Teresa", Tirana, Albania.
Liliana GarneataCarol Davila University of Medicine and Pharmacy, Bucharest, Romania.ORCID 0000-0002-1464-0741
Dajana KaticicCroatian Society of Nephrology, Dialysis and Transplantation, Croatia.
Roser TorraInherited Kidney Diseases, Nephrology Department, Fundació Puigvert, Institut de Recerca Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.ORCID 0000-0001-8714-2332
Alberto OrtizDepartment of Nephrology and Hypertension, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain.ORCID 0000-0002-9805-9523
Vianda S StelERA Registry, Amsterdam UMC location University of Amsterdam, Medical Informatics, Amsterdam, The Netherlands.ORCID 0000-0002-0007-1947

Funding

European Renal Association
6 · The paper itself

Abstract

background and hypothesisKidney replacement therapy (KRT) practices in Europe are heterogeneous, with apparent differences between Western and Central/Eastern Europe. However, time trends in KRT incidence and prevalence in Central and Eastern Europe have not been previously reported. Therefore, we aimed to describe trends in incidence and prevalence of KRT in Central and Eastern Europe from 2010 to 2021.

methodsData on incident and prevalent KRT patients from 19 Central and Eastern European countries between the years 2010 and 2021 were derived from the European Renal Association (ERA) Registry. Time trends were calculated using JoinPoint regression.

resultsOverall, KRT incidence increased at 1.5% [95% confidence interval (CI): +0.7 to +2.6%] per year from 106.3 per million population (pmp) in 2010 to 119.6 pmp in 2019. However, trends differed within the region. While in Bosnia and Herzegovina KRT incidence significantly decreased from 2010 to 2019, it remained stable in nine and increased in eight countries. The overall KRT prevalence increased at 5.1% (95% CI: +4.5 to +5.7%) per year from 426.2 pmp in 2010 to 651.2 pmp in 2019. KRT prevalence increased in all countries, except for Belarus where it remained stable, and was mainly attributable to increases in the prevalence of kidney transplantation. The COVID-19 pandemic did not have a major impact on KRT incidence and prevalence in the region, as most trends remained until 2021.

conclusionsAlthough we found an overall increase in KRT incidence and prevalence in the region, large country variations remain, much larger than observed in Western Europe. The results of this study can help to define country-specific priorities for the optimization of KRT care in Central and Eastern Europe.

Indexed as

Kidney Failure, ChronicRegistriesRenal Replacement TherapyAdultAgedEastern European PeopleEuropeEurope, EasternFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedPrevalencePrognosisCentral and Eastern Europedialysisincidencekidney transplantationprevalence

Identifiers

PMID41499147
PMCPMC13403274

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.