Evidence map›Paper›PMID 41499099›Full record

ArticleACS nano2026

Intracellular Localization of DNA-Wrapped Single-Walled Carbon Nanotube Sensors for Nitric Oxide Detection in Triple-Negative Breast Cancer Cells.

Portia N A Plange, Sofia E Morales-Mendivelso, Trisam Sapkota, Nicky N D Tagoe, Bara Altartouri, Nicole M Iverson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS nano, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Portia N A PlangeDepartment of Biological Systems Engineering, College of Agricultural Sciences and Natural Resources, University of Nebraska-Lincoln, Lincoln, Nebraska 68504, United States.ORCID 0000-0002-1410-6311
Sofia E Morales-MendivelsoDepartment of Biological Systems Engineering, College of Agricultural Sciences and Natural Resources, University of Nebraska-Lincoln, Lincoln, Nebraska 68504, United States.
Trisam SapkotaDepartment of Biological Systems Engineering, College of Agricultural Sciences and Natural Resources, University of Nebraska-Lincoln, Lincoln, Nebraska 68504, United States.
Nicky N D TagoeDepartment of Chemical and Biomolecular Engineering, University of Nebraska-Lincoln, Lincoln, Nebraska 68588, United States.
Bara AltartouriDepartment of Biochemistry and Nebraska Center for Biotechnology, University of Nebraska-Lincoln, Lincoln, Nebraska 68588, United States.ORCID 0000-0002-9148-640X
Nicole M IversonDepartment of Biological Systems Engineering, College of Agricultural Sciences and Natural Resources, University of Nebraska-Lincoln, Lincoln, Nebraska 68504, United States.ORCID 0000-0002-5166-1410

Funding

Supplement for Equipment Purchase - Hyperspectral Near Infrared Confocal MicroscopeR35GM138245 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI IVERSON, NICOLE MARIE · 2020 to 2024
$2.0M
NIGMS NIH HHS R35 GM138245
6 · The paper itself

Abstract

Spatiotemporal sensors capable of monitoring analyte activity in subcellular compartments of cells are critical to advancing our understanding of complex disease progression. Nitric oxide (NO) plays a key role in tumor progression, yet its precise function remains unclear due to its bimodal effect, which is influenced by its subcellular distribution. Factors such as membrane permeability, NO reactivity, and redox states of intracellular compartments may determine whether NO promotes or suppresses tumor growth. Current sensors are limited in providing spatial and temporal information about NO in live cells. Single-walled carbon nanotubes (SWNT), specifically (6,5) SWNT functionalized with (AT)

Indexed as

Biosensing TechniquesDNANanotubes, CarbonNitric OxideTriple Negative Breast NeoplasmsCell Line, TumorFemaleFluorescent Chemosensor CompoundsHumansDNAFluorescent Chemosensor CompoundsNanotubes, CarbonNitric OxideColocalizationlysosomemitochondrianitric oxideSingle-walled carbon nanotubesspatiotemporal sensor

Identifiers

PMID41499099
PMCPMC12915888

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.