Evidence map›Paper›PMID 41499089›Full record

ReviewOphthalmology and therapy2026

Update on XEN Gel Stent: A Narrative Review on Indications, Surgical Technique, and Postoperative Management.

Elena Millá Griñó, Rafael Giménez Gómez, José Manuel Larrosa Poves, Jorge Vila Arteaga, Almudena Asorey García, Fernando Giacomini, Vanessa Vera

Abstract readReview
In one paragraph

Review in Ophthalmology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elena Millá GriñóDepartment of Ophthalmology, Hospital Clinic, Barcelona, Spain.
Rafael Giménez GómezDepartment of Ophthalmology, Hospital Reina Sofía, Córdoba, Spain.
José Manuel Larrosa PovesDepartment of Ophthalmology, Hospital Universitario Miguel Servet, Saragossa, Spain.
Jorge Vila ArteagaDepartment of Ophthalmology, Hospital La Fe, Valencia, Spain.
Almudena Asorey GarcíaAbbvie Spain S.L.U., Avenida de Burgos 91, Madrid, Spain. Almudena.asorey@abbvie.com.
Fernando GiacominiAbbvie Spain S.L.U., Avenida de Burgos 91, Madrid, Spain.
Vanessa VeraAbbVie S.L.U., North Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite topical ocular hypotensive treatment and selective laser trabeculoplasty being the preferred first-line treatment modalities for lowering intraocular pressure, many patients require surgery for further controlling glaucoma progression. The XEN stent is a surgical device designed for the management of glaucoma where previous medical treatments have failed, offering greater predictability and fewer vision-threatening complications compared to trabeculectomy or tube shunts. This comprehensive and narrative review aims to assess different aspects related to XEN implant, including its efficacy, patient profile, surgical technique, and the identification of potential predictors of clinical outcomes. Additionally, this paper describes the most frequently reported adverse events associated with the XEN implant, with the objective of reducing their incidence through a comprehensive understanding of their underlying pathophysiology. Moreover, the authors draw on both existing literature and their clinical experience to provide recommendations for the optimization of the use of this implant.

Indexed as

GlaucomaHypotonyMIBSMinimally invasive bleb surgerySuccessTrabeculectomyXEN

Identifiers

PMID41499089
PMCPMC12901802

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.