ArticleJournal of community health2026
Human Papillomavirus Vaccine Uptake and its Determinants among Parents of Adolescent Girls in Tanga city, Tanzania.
Article in Journal of community health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Human papillomavirus (HPV) is the leading cause of cervical cancer, a major public health challenge in Tanzania. National and global efforts continue to prioritise HPV vaccination; however, coverage remains suboptimal. In Tanga City, no prior data exists on HPV vaccine uptake. This study assesses HPV vaccine uptake and factors influencing parental acceptance among girls aged 9-14 years. A community-based cross-sectional study was conducted among 409 parents or guardians selected through multistage cluster sampling. Data were collected using structured interviewer-administered questionnaires. Descriptive statistics determined uptake, while bivariate and multivariate logistic regression were used to identify predictors of HPV vaccine uptake, with significance set at p < 0.05. HPV vaccine uptake was 57.2%. Parental age < 30 years (AOR = 0.411; 95% CI: 0.221-0.765), secondary education (AOR = 0.340; 95% CI: 0.124-0.930) and living within 5 km of a vaccination point (AOR = 0.478; 95% CI: 0.246-0.929), were associated with lower uptake, while being married and school-based vaccination increased uptake (AOR = 2.898; 95% CI: 1.723-4.876; AOR = 10.275; 95% CI: 5.518-19.133). Knowledge, attitudes, and healthcare worker recommendation showed no significant association in the multivariate model. HPV vaccine uptake in Tanga remains below national and global targets (90%). Parental demographics, access-related factors, and school-based delivery play a central role in uptake. Strengthening school-based vaccination, enhancing parent engagement, particularly among younger and more educated parents, and addressing contextual barriers may improve coverage and contribute to cervical cancer prevention efforts in Tanzania.
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