Evidence map›Paper›PMID 41498999›Full record

ArticleIrish journal of medical science2026

Efficacy and safety of micropulse transscleral cyclophotocoagulation in glaucoma: a two-year retrospective audit cohort.

Mahmoud Eissa, Abdulrahman Mohamed, Salma Dahshan, Ahmed Elsayed

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Article in Irish journal of medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mahmoud EissaDepartment of Ophthalmology, Dumfries and Galloway NHS Trust, Mountainhall Treatment Centre, Bankend Road, Dumfries, DG1 4AP, UK.
Abdulrahman MohamedDepartment of Ophthalmology, Dumfries and Galloway NHS Trust, Mountainhall Treatment Centre, Bankend Road, Dumfries, DG1 4AP, UK.
Salma DahshanAhmed Maher Teaching Hospital, Cairo, Egypt.
Ahmed ElsayedDepartment of Ophthalmology, Dumfries and Galloway NHS Trust, Mountainhall Treatment Centre, Bankend Road, Dumfries, DG1 4AP, UK. Ahmed.Elsayed@nhs.scot.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo retrospectively evaluate the efficacy and safety of Micropulse Transscleral Cyclophotocoagulation (MP-TSCPC) in reducing intraocular pressure (IOP) and the number of glaucoma medications in patients with different types of glaucoma over a two-year period.

methodsThis retrospective audit included 52 eyes from 32 patients treated with MP-TSCPC at Mountainhall Treatment Centre, Dumfries, UK, between August 2021 and September 2023. Standard treatment parameters included 2500 mW power applied for 10 s per quadrant across 9 cycles. Primary outcomes were changes in IOP and the number of glaucoma medications. Secondary outcomes included postoperative complications and changes in the mean deviation of the visual field (MD).

resultsThe mean preoperative IOP was 21.4 mmHg, which significantly decreased postoperatively to 11.9 mmHg at 4 weeks, 12.75 mmHg at 3 months, 13.4 mmHg at 1 year, and 14.03 mmHg at 2 years. The median IOP reduction at 1 year was 5.0 mmHg with statistical significance (p < 0.0001). The average number of topical medications declined from 2.21 eye drops to 1.58 eye drops. No statistically significant change was observed in visual field MD (p = 0.4838), though disease progression appeared to stabilize (mean MD: -7.1 dB). Complications were infrequent and included mild anterior uveitis (n = 12), cystoid macular edema, recurrence of herpetic keratitis and severe ocular inflammation (n = 1).

conclusionMP-TSCPC is a safe and effective procedure for medium-term IOP control, particularly in patients with primary open-angle glaucoma. It significantly reduces IOP and medication dependency, with a low complication profile. However, outcomes are more variable in secondary glaucoma, especially uveitic cases. These findings support the growing role of MP-TSCPC as a minimally invasive treatment option for glaucoma.

Indexed as

Ciliary BodyGlaucomaLaser CoagulationAdultAgedFemaleHumansIntraocular PressureMaleMiddle AgedRetrospective StudiesScleraTreatment OutcomeCyclophotocoagulationGlaucomaIOP reductionMicropulse laser therapyOcular hypertension

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.