ReviewEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2026
Role of polyetheretherketone (PEEK) in arthroplasty and orthopaedics: a review of biomechanical properties, surface modifications, and clinical outcomes.
Review in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Machine learning driven forward-reverse design of Ag-ZnO-PEEK nanocomposites for sustainable biomass and lipid enhancement in Chlorella vulgaris AK_123 with integrated anti-bacterial activity.Scientific reports · 2026Article
- The Influence of Mechanical and Microstructural Characteristics on the Durability of a Femoral Implant Made of Different Alloys.Journal of functional biomaterials · 2026Article
- Polyetheretherketone (PEEK) in Cranial Vault Reconstruction: A Review of Alloplastic Materials, Clinical Performance, and Institutional Experience.Bioengineering (Basel, Switzerland) · 2026Article
- Biocompatibility, Durability, and Stability Assessment of an Unconstrained Metacarpophalangeal Joint Prosthesis With Zirconia (ZrOJournal of hand surgery global online · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPolyetheretherketone (PEEK) has gained attention as an alternative to metallic implants in orthopaedic applications, including arthroplasty, due to its mechanical properties and biocompatibility. This review evaluates the role of PEEK in arthroplasty and other orthopaedic applications by analysing its biomechanical characteristics, surface modifications, and clinical outcomes
methodsA comprehensive literature review was conducted using PubMed, PubMed Central (PMC), Scopus, and Embase. Eligible studies included randomised controlled trials, cohort studies, preclinical research, and systematic reviews.
resultsPEEK's elastic modulus (3-4 GPa) closely matches that of human cortical bone, potentially reducing stress shielding and enhancing osseointegration. Its inherent radiolucency improves imaging capabilities, while various surface modification techniques, including hydroxyapatite coatings and nanopatterning, have been developed to enhance bone integration. Despite positive preclinical outcomes, clinical studies are predominantly focused on short- to mid-term results, with limited long-term data on implant survivorship and complications.
conclusionsWhile PEEK shows promise in orthopaedic applications, further research is necessary to establish its clinical efficacy relative to traditional metals. Addressing the current gaps in long-term studies, regulatory challenges, and manufacturing processes will be crucial for the broader adoption of PEEK implants in orthopaedic surgery. This review highlights the ongoing evolution of PEEK in the field and suggests directions for future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.