ArticleChemistry (Weinheim an der Bergstrasse, Germany)2026
Expanding the Toolbox for Inducible Protein Expression With Automation-enabled Generation of Glycomimetics.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Inducible protein expression is a cornerstone of many aspects of industrial and molecular biotechnological processes. However, limited availability of inducible transcription factors can reduce our ability to control expression at a population level. The design and synthesis of a powerful inducer containing a fucose is demonstrated to induce protein expression through the lac operon only in cells with the ability to selectively de-fucosylate them. Batch and automated continuous-flow processes are reported for the syntheses of both 2'-fucosyl isopropyl-β-D-thiogalactopyranose (2'F-IPTG) and isobutyl-C-galactoside (2'F-IBCG) mimics. Fucosylation of the inducer allowed for fucosidase-dependent expression of a reporter protein, providing an additional layer of control over inducible gene expression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.