Evidence map›Paper›PMID 41498514›Full record

ReviewLab on a chip2026

Paper-based microfluidics for wearable soft bioelectronics.

Feng Zhang, Ganggang Zhao, Qunle Ouyang, Sicheng Chen, Zheng Yan

Abstract readReview
In one paragraph

Review in Lab on a chip, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Feng ZhangDepartment of Chemical and Biomedical Engineering, University of Missouri, Columbia, MO, USA. yanzheng@missouri.edu.ORCID 0009-0003-9721-694X
Ganggang ZhaoDepartment of Mechanical and Aerospace Engineering, University of Missouri, Columbia, MO, USA.
Qunle OuyangDepartment of Mechanical and Aerospace Engineering, University of Missouri, Columbia, MO, USA.
Sicheng ChenDepartment of Chemical and Biomedical Engineering, University of Missouri, Columbia, MO, USA. yanzheng@missouri.edu.
Zheng YanDepartment of Chemical and Biomedical Engineering, University of Missouri, Columbia, MO, USA. yanzheng@missouri.edu.ORCID 0000-0001-5968-0934

Funding

Multifunctional Porous Soft Materials for User-Friendly Skin-Interfaced Bimodal Cardiac Patches with Long-Term Biocompatibility and Antimicrobial PropertyR01EB033371 · NIBIB · UNIVERSITY OF MISSOURI-COLUMBIA · PI YAN, ZHENG · 2022 to 2025
$2.6M
NIBIB NIH HHS R01 EB033371
6 · The paper itself

Abstract

Wearable biosensing technologies are transforming healthcare by enabling continuous, real-time monitoring of physiological states at the point of care. Flexible microfluidics, particularly paper-based microfluidics, serve as critical interfaces between the body and soft electronics, enabling precise, capillary-driven, and non-invasive biofluid handling for real-time and clinically informative diagnostics. In this review, we discuss the fundamentals of paper-based microfluidics, highlighting critical considerations in material design, structural regulation, and interface engineering for precise capillary flow manipulation. We revisit fabrication techniques and key milestones in developing paper-based microfluidic devices, emphasizing innovative on-skin applications for wearable biofluid sampling, biosensing, and disease diagnostics. Finally, we outline persistent challenges that need to be addressed in the clinical translation of paper-based microfluidics for wearable healthcare and discuss future perspectives, including advances in paper materials engineering, integration with machine learning algorithms, and Internet-of-Things, to enable the next-generation personalized wearable healthcare solutions.

Indexed as

Biosensing TechniquesLab-On-A-Chip DevicesMicrofluidic Analytical TechniquesPaperWearable Electronic DevicesDigital HealthEquipment DesignHumans

Identifiers

PMID41498514
PMCPMC12777650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.