Evidence map›Paper›PMID 41498492›Full record

ReviewJournal of child psychology and psychiatry, and allied disciplines2026

Practitioner Review: Infant mental health meets cell and molecular biology - a look to the future.

Charles H Zeanah, Megan Hare, Katherine Cowhey, Stacy S Drury

Abstract readReview
In one paragraph

Review in Journal of child psychology and psychiatry, and allied disciplines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Charles H ZeanahTulane University School of Medicine, New Orleans, LA, USA.ORCID 0000-0002-7004-6819
Megan HareTulane University School of Medicine, New Orleans, LA, USA.
Katherine CowheyTulane University School of Medicine, New Orleans, LA, USA.
Stacy S DruryBoston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA major research effort in the past two decades has begun to illuminate how experience 'gets under the skin' - that is - the cellular and molecular processes that are associated with adversity and resilience.

methodsWe selectively review three areas of this research: epigenetics, especially DNA methylation, telomere length, and inflammatory processes, and consider the implications of this work for better understanding the effects of adversity and pathways of recovery.

resultsBecause infant mental health practitioners focus on children in the earliest years of life, they are well positioned to favorably alter the developmental trajectories of children experiencing or at risk for maladaptation. In addition to helping us develop more individually effective treatments, we consider other ways in which research advances in cell and molecular biology may be especially important to infant mental health practitioners in the future.

conclusionsBetter understanding these processes will enhance effectiveness and potentially enlarge the scope of our practice.

Indexed as

Adverse Childhood ExperiencesDNA MethylationEpigenesis, GeneticMental HealthHumansInfantbiologyEarly life experience

Identifiers

PMID41498492
PMCPMC13265628

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.