ArticleEmerging microbes & infections2026
Evaluation of the vaccine candidate ASFV-MEC-01: safety, efficacy, transmission dynamics, and assessment of reversion to virulence.
Article in Emerging microbes & infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Live-Attenuated Vaccines Against African Swine Fever: Strategies, Lessons, and Prospects.Biology · 2026Review
- African Swine Fever: Vaccine Advancement and Major Gaps.Microorganisms · 2026Review
Corrections and comments
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Authors and funding
27 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
African swine fever (ASF) is a highly contagious and often fatal disease that poses a serious threat to global pig farming and food security. Despite decades of research, a safe and effective vaccine has not yet been widely implemented. In our previous study, we introduced ASFV-MEC-01, a novel live attenuated vaccine candidate developed through serial passaging of a field isolate in CA-CAS-01-A cells and subsequently characterized. In the present study, we further evaluated the safety parameters of ASFV-MEC-01. Specifically, we reaffirmed the safety and protective efficacy of ASFV-MEC-01 against a highly virulent Vietnamese ASFV strain. Notably, safety assessments were also conducted in pregnant sows. Furthermore, ASFV-MEC-01 showed no evidence of horizontal transmission to sentinel pigs and did not revert to virulence after consecutive
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