ArticleClinical, cosmetic and investigational dermatology2025
The Combination of Mineral Salts and Natural Antioxidants Agents Is Highly Effective in Atopic Dermatitis.
Article in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Itching, Ionic Channels, Immune System, Magnesium and Antioxidants.Clinical, cosmetic and investigational dermatology · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Intrinsic atopic dermatitis (AD) is a chronic inflammatory skin disease with pruritus and eczematous lesions of skin. A long-lasting cycle of itch-scratch roots results in substantial morbidities and discomfort. Treatment of patients with moderate to severe dermatitis is a challenge. To evaluate the efficacy of a treatment based on mineral salts and natural antioxidants agents in patients with AD. Patients and Methods: In this prospective study, 34 patients with AD were treated for 14 days. Patients were evaluated before and after treatment. The effects were studied by the following clinical measurements: Eczema Area and Severity Index (EASI), Scoring Atopic Dermatitis (SCORAD), Body Surface Area (BSA), and Validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD). Patient-reported measurements were also assessed: Patient-Oriented Eczema Measure (POEM), Dermatology Life Quality Index (DLQI), and the pruritus Numeric Rating Scale (NRS). Biopsies were performed in 10 patients and immunohistochemistry tests in 7 patients. Results: All clinical and patient-reported measurements showed a strong difference before and after treatment. The epidermis thickness was significantly reduced, as well as the lymphocyte infiltration and the reduction of CD3, CD4, CD8, CD20 and CD117 cells. No adverse events were observed. Conclusion: This study shows that the severity of intrinsic dermatitis was drastically reduced with the treatment of mineral salts and natural antioxidants agents. This topic treatment was very well tolerated without adverse events.
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