Evidence map›Paper›PMID 41498104›Full record

ArticleJournal of toxicology2025

Lower Toxicity of the Essential Oils With Repellent Potential Compared to Diethyltoluamide and Cypermethrin on

Heber Silva-Díaz, Angie Vilma Serrato-Monja, Emma Vanesa Arriaga-Deza, Lizzie Karen Becerra-Gutiérrez

Abstract read
In one paragraph

Article in Journal of toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Heber Silva-DíazFaculty of Human Medicine, University of San Martín de Porres, Chiclayo, Peru, usmp.edu.pe.ORCID https://orcid.org/0000-0001-8263-9673
Angie Vilma Serrato-MonjaFaculty of Biological Sciences, Pedro Ruiz Gallo National University, Lambayeque, Peru.ORCID https://orcid.org/0009-0008-2504-9472
Emma Vanesa Arriaga-DezaFaculty of Human Medicine, University of San Martín de Porres, Chiclayo, Peru, usmp.edu.pe.ORCID https://orcid.org/0000-0002-5384-6152
Lizzie Karen Becerra-GutiérrezFaculty of Human Medicine, University of San Martín de Porres, Chiclayo, Peru, usmp.edu.pe.ORCID https://orcid.org/0000-0001-8243-7932

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the acute toxicity of essential oils with repellent potential, diethyltoluamide (DEET), and cypermethrin on Methods: Randomized preclinical trial with a factorial and controlled arrangement on three essential oils ( Results: Essential oils at concentrations of 0.1% and 1% showed similar toxicity to each other (mortality of 10%-20%) but significantly lower compared to cypermethrin and DEET (mortality of 100%). However, essential oils at 10% reached median mortality rates above 70%. Likewise, similar effects were observed at concentrations of 0.1% and 1.0% and at 24 and 48 h. The LC 50 at 24 h was 7.8% (CI 95%: 5.2-9.8), 6.1% (CI 95%: 4.9-7.4), and 9.8% (CI 95%: 8.9-10.6) for Conclusions: The evaluated essential oils showed lower acute toxicity compared to DEET and cypermethrin, depending on concentration and time.

Indexed as

DEETinsect repellentsisopoda (MeSH-NLM)oilstoxicityvolatile

Identifiers

PMID41498104
PMCPMC12767039

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.