Evidence map›Paper›PMID 41498021›Full record

ReviewMediators of inflammation2025

Emerging Topics and Trends in Neutrophil Extracellular Traps in ARDS: A Bibliometric and Visual Analysis.

Yike Wang, Zixin Luo, Shaoyu Fu, Qianduo Li, Zhiyuan Zhang, Nan Huang, Kang Zou, Lingyan Zou

Abstract readReview
In one paragraph

Review in Mediators of inflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yike WangThe First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi Province, China, gmu.cn.ORCID https://orcid.org/0009-0007-0719-6797
Zixin LuoThe First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi Province, China, gmu.cn.ORCID https://orcid.org/0009-0009-2573-8830
Shaoyu FuThe First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi Province, China, gmu.cn.ORCID https://orcid.org/0009-0009-2976-7137
Qianduo LiThe First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi Province, China, gmu.cn.ORCID https://orcid.org/0009-0003-2338-9960
Zhiyuan ZhangThe First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi Province, China, gmu.cn.ORCID https://orcid.org/0009-0008-2995-6889
Nan HuangThe First Clinical Medical College, Gannan Medical University, Ganzhou, 341000, Jiangxi Province, China, gmu.cn.ORCID https://orcid.org/0009-0007-3781-1332
Kang ZouDepartment of Critical Care Medicine, The First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, Jiangxi Province, China, gmu.cn.ORCID https://orcid.org/0000-0002-4959-1951
Lingyan ZouDepartment of Respiratory and Critical Care Medicine, Ganzhou Hospital-Nanfang Hospital, Southern Medical University (Ganzhou People's Hospital), Ganzhou, 341000, Jiangxi Province, China, fimmu.com.ORCID https://orcid.org/0000-0001-9517-8765

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute respiratory distress syndrome (ARDS) is a critical illness with significant impacts on human respiratory health. Neutrophil extracellular traps (NETs), secreted by neutrophils, play dual roles in immune defense and tissue inflammation. Recent studies have highlighted the association between NETs and ARDS, yet no comprehensive bibliometric analysis has been conducted in this field. This study aims to analyze the research progress and evolving hot spots related to NETs in ARDS through bibliometric methods. Methods: Articles published between 2011 and 2024 were retrieved from the Web of Science Core Collection (WoSCC), PubMed, and Embase. Data analysis was performed using visualization tools such as VOSviewer, CiteSpace, and Microsoft Office Excel 2021. Results: A total of 328 articles were analyzed. The annual publication trend in this field has shown a steady increase, with China and the United States leading in research output. Frontiers in Immunology stands out for its high publication volume and citation count, indicating strong reference value. The most prolific author is Zhang, Hao from Zhongshan Hospital, Fudan University, while Egeblad, Mikala from Cold Spring Harbor Laboratory holds the highest citation count. Inflammatory response is a research focus in this field, and the association between NETs and thrombus formation represents an emerging research hotspot within the domain. Research and development of NETs-targeted therapies for acute lung injury (ALI) and ARDS is an important direction for future research. Conclusion: This bibliometric analysis comprehensively summarizes research progress and hotspot evolution in NETs-related ARDS studies, providing valuable insights for researchers and inspiring future research directions.

Indexed as

Extracellular TrapsNeutrophilsRespiratory Distress SyndromeBibliometricsHumansARDSCiteSpaceNETsVOSviewerWoSCC

Identifiers

PMID41498021
PMCPMC12767411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.