Evidence map›Paper›PMID 41498019›Full record

ArticleBJA open2025

North American and European practices for opioid-sparing and opioid-free anaesthesia: a cross-sectional survey.

Yann Gricourt, Nancy M Boulos, Yann Daoulas, Tristan Grogan, Brenton Alexander, Myriam Mezzarobba, Philippe Cuvillon, Esther M Pogatzki-Zahn, Helene Beloeil, Maxime Cannesson and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BJA open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yann GricourtDepartment of Anesthesiology and Perioperative Medicine, Nimes University Hospital, Nimes, France.
Nancy M BoulosDepartment of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Yann DaoulasDepartment of Anesthesiology and Intensive Care Medicine, Lapeyronie University Hospital, Montpellier, France.
Tristan GroganDepartment of Medicine Statistics Core, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Brenton AlexanderDepartment of Anesthesiology & Perioperative Medicine, University of California San Diego, La Jolla, CA, USA.
Myriam MezzarobbaDepartment of Biostatistics, Epidemiology, Public Health and Innovation in Methodology, CHU Nimes, IDESP, INSERM, University of Montpellier, Nimes, France.
Philippe CuvillonDepartment of Anesthesiology and Perioperative Medicine, Nimes University Hospital, Nimes, France.
Esther M Pogatzki-ZahnDepartment of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Muenster, Muenster, Germany.
Helene BeloeilUniversity of Rennes, CHU Rennes, Inserm, OSS 12142, CIC 1414, Anaesthesia and Intensive Care Department, Rennes, France.
Maxime CannessonDepartment of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Patrice ForgetIMAGINE UR UM 103, Montpellier University, Anaesthesia Critical Care, Emergency and Pain Medicine Division, Nîmes University Hospital, Nîmes, France.
Alexandre JoostenDepartment of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.

Funding

Multidisciplinary Anesthesiology and Perioperative Medicine Research Training ProgramT32GM148369 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Maxime Cannesson, Mansoureh Eghbali · 2023 to 2026
$1.1M
NIGMS NIH HHS T32 GM148369
6 · The paper itself

Abstract

Background: Opioids remain central to perioperative analgesia but concerns about the growing opioid crisis and adverse effects have prompted revaluation of their role. Opioid-sparing anaesthesia and opioid-free anaesthesia (OFA) have emerged as alternatives, yet their clinical adoption remains uncertain. This survey assessed adoption and perceptions among anaesthesiologists in North America and Europe. Methods: A 26-question cross-sectional, web-based survey was distributed via email to members of the American, European, and French Societies of anaesthesiologists. The survey assessed routine use of opioid-sparing techniques, defined as the regular use of non-opioid analgesics and adjuncts to minimise intraoperative opioid use in the past month. We hypothesised that fewer than 50% of anaesthesiologists routinely used these techniques during this period. Results: The overall response rate was 2% among ASA members (614/31 000) and 12% among European Society of Anaesthesiology and Intensive Care (ESAIC) members (414/3500). Concern about opioid use was reported as high in ESAIC and ASA members (90% Conclusions: Interest in opioid-sparing anaesthesia and OFA is widespread, but routine use remains modest and varies by region. Regional perceptions, institutional protocols, and confidence in evidence appear to influence implementation.

Indexed as

analgesiadexmedetomidineintraoperative managementketaminemultimodal analgesiaopioid crisisopioid-free anaesthesiaregional anaesthesia

Identifiers

PMID41498019
PMCPMC12767688

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.