ReviewFood chemistry: X2026
Deep eutectic solvents as an emerging platform for microbial carotenoids extraction: State of the art, prospects, and challenges.
Review in Food chemistry: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microbial carotenoids are promising alternatives to synthetic ones in food, cosmetics, nutraceuticals, and pharmaceuticals, offering antioxidant, anti-aging, and anti-cancer benefits. However, the conventional extraction methods commonly used for carotenoids often rely on petrochemical solvents, raising environmental and health concerns. In this context, deep eutectic solvents (DESs) have emerged as sustainable alternatives due to their low toxicity, cost-effectiveness, ease of preparation, biodegradability, recyclability, and excellent compatibility. This review discusses the history, classification, toxicity, and biodegradability of DESs, along with recent advances in microbial carotenoid recovery, focusing on pretreatment, extraction, and underlying mechanisms, followed by the discussions on sustainability assessment and current technological challenges. While DES-based processes show significant potential within green chemistry, their feasibility for large-scale, commercial applications remains to be validated. By providing a critical overview, this study aims to guide further research and development in eco-friendly downstream processing of microbial carotenoids, bridging the gap between scientific investigation and industrial practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.