Evidence map›Paper›PMID 41497922›Full record

ArticleCureus2025

Root Maturity as a Determinant of Post-traumatic Endodontic Outcomes: A Comparative Case Report.

Nevia Pradeep, Jemi Wilson, Parvathy Kumaran, Balagopal Varma R, Suresh Kumar J, Arun Mamachan Xavier, Malini Venugopal, Nishna Thankappan, Cherupally K Krishnan Nair, Sheena P Kochumon

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nevia PradeepPediatric Dentistry, Amrita Vishwa Vidyapeetham, Kochi, IND.
Jemi WilsonPediatric Dentistry, Amrita Vishwa Vidyapeetham, Kochi, IND.
Parvathy KumaranPediatric Dentistry, Amrita Vishwa Vidyapeetham, Kochi, IND.
Balagopal Varma RPediatric Dentistry, Amrita Vishwa Vidyapeetham, Kochi, IND.
Suresh Kumar JPediatric Dentistry, Amrita Vishwa Vidyapeetham, Kochi, IND.
Arun Mamachan XavierPediatric Dentistry, Amrita Vishwa Vidyapeetham, Kochi, IND.
Malini VenugopalPediatric Dentistry, Amrita Vishwa Vidyapeetham, Kochi, IND.
Nishna ThankappanPediatric Dentistry, Amrita Vishwa Vidyapeetham, Kochi, IND.
Cherupally K Krishnan NairHealth Sciences, Amrita Vishwa Vidyapeetham, Kochi, IND.
Sheena P KochumonPediatric and Child Health/Genomics/Health Sciences and Research, Amrita Vishwa Vidyapeetham, Kochi, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tooth avulsion and intrusion are severe traumatic dental injuries that often lead to tooth loss and root resorption. The main determinants of prognosis include root maturity, extra-alveolar time, and the timing and type of treatment. This study presents a comparative analysis of the healing responses in two pediatric cases following delayed and complicated replantation, with a focus on how the maturity of the tooth root influenced the outcomes. The case report details two pediatric cases with significantly different healing trajectories after replantation. Case 1 involves an eight-year-old boy with an avulsed immature permanent left central incisor (21) that was replanted after approximately six hours of extra-oral time. A revascularization procedure was performed two weeks post-replantation. While limited external resorption was noted at three months, it spontaneously arrested by the six-month follow-up. Case 2 presents a 10-year-old boy with severe intrusion of mature maxillary central incisors (11, 21), which were surgically repositioned and replanted. Root canal treatment was initiated at the second week, but radiographic evidence of progressive resorption was observed on both teeth by the end of six weeks. The immature tooth (Case 1) demonstrated a favorable healing response, characterized by revascularization and the spontaneous arrest of resorption. In contrast, the mature teeth (Case 2) experienced ongoing, progressive resorption despite conventional endodontic intervention. Root maturity significantly influences the regenerative potential and resorption outcome in replanted teeth. Immature teeth with open apices possess a greater capacity for healing and may benefit from regenerative endodontic approaches, even in instances of delayed replantation. Conversely, mature teeth with closed apices have a more guarded prognosis, with a higher propensity for progressive resorption following severe traumatic injuries.

Indexed as

closed apexdental traumaexternal inflammatory resorptionopen apexpediatric dentistryrevascularizationroot resorptiontooth replantation

Identifiers

PMID41497922
PMCPMC12766135

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.