Evidence map›Paper›PMID 41497901›Full record

ArticleMaterials today. Bio2026

Multiscale hierarchical surface structuring of zirconia using femtosecond laser and chemical etching: implications for cell response and antibacterial performance.

Nerea Garcia-de-Albeniz, Daniel W Müller, Frank Mücklich, Maria-Pau Ginebra, Emilio Jiménez-Piqué, Carlos Mas-Moruno

Abstract read
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Advanced Technologies for Processing Functional Biomaterials.Journal of functional biomaterials · 2026
    Article
  3. Isolation and characterization of a novelFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nerea Garcia-de-AlbenizCenter for Structural Integrity, Reliability and Micromechanics of Materials (CIEFMA), Department of Materials Science and Engineering, Universitat Politècnica de Catalunya. BarcelonaTech (UPC), Av. Eduard Maristany, 16, 08019, Barcelona, Spain.
Daniel W MüllerFunctional Materials, Department of Materials Science and Engineering, Saarland University, 66123, Saarbrücken, Germany.
Frank MücklichFunctional Materials, Department of Materials Science and Engineering, Saarland University, 66123, Saarbrücken, Germany.
Maria-Pau GinebraBiomaterials, Biomechanics and Tissue Engineering Group (BBT), Department of Materials Science and Engineering and Institute for Research and Innovation in Health (IRIS), Universitat Politècnica de Catalunya. BarcelonaTech (UPC), Av. Eduard Maristany, 16, 08019, Barcelona, Spain.
Emilio Jiménez-PiquéCenter for Structural Integrity, Reliability and Micromechanics of Materials (CIEFMA), Department of Materials Science and Engineering, Universitat Politècnica de Catalunya. BarcelonaTech (UPC), Av. Eduard Maristany, 16, 08019, Barcelona, Spain.
Carlos Mas-MorunoBiomaterials, Biomechanics and Tissue Engineering Group (BBT), Department of Materials Science and Engineering and Institute for Research and Innovation in Health (IRIS), Universitat Politècnica de Catalunya. BarcelonaTech (UPC), Av. Eduard Maristany, 16, 08019, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates a novel strategy combining ultrashort pulsed-direct laser interference patterning (USP-DLIP) and chemical etching to create hierarchically micro- and nanorough topographies on zirconia with improved cell-instructive and antibacterial properties. Linear (L3) and grid (G3) micropatterns of 3 μm periodicity were fabricated via USP-DLIP, and subsequently treated with hydrofluoric acid to introduce an additional homogeneous nanotopography across the patterns. The individual and combined effects of micropatterning and etching on biological responses were evaluated using human mesenchymal stem cells (hMSCs) and two bacterial strains (

Indexed as

AntibacterialChemical etchingDental implantsLaser patterningNanotopographyOsteointegrationTopographyZirconia

Identifiers

PMID41497901
PMCPMC12767873

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.