Evidence map›Paper›PMID 41497729›Full record

ReviewJournal of ophthalmology2025

Ocular Lesions Related to COVID-19 and Its Vaccines.

Tao Liu, Mengyao Li, Lin Zhu, Ruyu Liang, Peng Zhang, Xiaoli Liu

Abstract readReview
In one paragraph

Review in Journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tao LiuOphthalmologic Center of the Second Hospital, Jilin University, Ziqiang Street 218, Changchun, China, jlu.edu.cn.
Mengyao LiOphthalmologic Center of the Second Hospital, Jilin University, Ziqiang Street 218, Changchun, China, jlu.edu.cn.
Lin ZhuOphthalmologic Center of the Second Hospital, Jilin University, Ziqiang Street 218, Changchun, China, jlu.edu.cn.
Ruyu LiangOphthalmologic Center of the Second Hospital, Jilin University, Ziqiang Street 218, Changchun, China, jlu.edu.cn.
Peng ZhangRadiology Department of the Second Hospital, Jilin University, Ziqiang Street 218, Changchun, China, jlu.edu.cn.
Xiaoli LiuOphthalmologic Center of the Second Hospital, Jilin University, Ziqiang Street 218, Changchun, China, jlu.edu.cn.ORCID https://orcid.org/0000-0002-5793-1872

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To review COVID-19 infection and COVID-19 vaccine-related ocular lesions. Methods: We carried out a systematic search in PubMed, Web of Science, Embase, and the Cochrane Library on COVID-19 and ophthalmology and reviewed the incidence, specific manifestations, and risk factors for COVID-19-related eye diseases and the relationship between the detection of COVID-19 in the conjunctiva and tears and eye involvement. Results: Conjunctivitis was the most common ocular lesion caused by 2019-nCoV infection, followed by uveitis and retinopathy. Conjunctivitis can be the first manifestation of COVID-19 infection and may be clinically related to the severity of pneumonia caused by COVID-19. In particular, conjunctivitis that occurs after pneumonia suggests that the patient has severe systemic disease. COVID-19 infection can cause uveitis, but the infection rate of COVID-19 in patients with uveitis is similar to that of the general population. Patients with uveitis need to reduce the dosage of systemic hormones and discontinue biological agents after being infected with COVID-19. Retinopathy caused by COVID-19 infection is mainly manifested as retinal microvascular disease, and the prognosis is good. SARS-CoV-2 detection in the conjunctiva and tears has high sensitivity and is of great value for disease diagnosis. Eye lesions caused by the COVID-19 vaccine, similar to other vaccines, have a low incidence and a good prognosis. Conclusion: COVID-19-related ocular lesions are mainly manifested as conjunctivitis, uveitis, and retinal microvascular changes. These diseases are somewhat self-limiting and have a good prognosis.

Indexed as

conjunctivitisCOVID-19eyeretinopathyuveitis

Identifiers

PMID41497729
PMCPMC12767034

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.