Evidence map›Paper›PMID 41497702›Full record

ArticleFood chemistry: X2025

Pectin-modified PCN-222 for detecting nitrofurazone residues with dual signals in livestock, poultry, and aquatic products.

Keyu Du, Jie Shen, Siyao Zhong, Hefei Wang, Yulou Qiu, Xuping Shentu, Xiaoping Yu, Zihong Ye, Haizhi Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Keyu DuKey Laboratory of Microbiological Metrology, Measurement & Bio-product Quality Security, State Administration for Market Regulation, College of Life Science, China Jiliang University, Hangzhou 310018, China.
Jie ShenKey Laboratory of Microbiological Metrology, Measurement & Bio-product Quality Security, State Administration for Market Regulation, College of Life Science, China Jiliang University, Hangzhou 310018, China.
Siyao ZhongKey Laboratory of Microbiological Metrology, Measurement & Bio-product Quality Security, State Administration for Market Regulation, College of Life Science, China Jiliang University, Hangzhou 310018, China.
Hefei WangKey Laboratory of Microbiological Metrology, Measurement & Bio-product Quality Security, State Administration for Market Regulation, College of Life Science, China Jiliang University, Hangzhou 310018, China.
Yulou QiuKey Laboratory of Microbiological Metrology, Measurement & Bio-product Quality Security, State Administration for Market Regulation, College of Life Science, China Jiliang University, Hangzhou 310018, China.
Xuping ShentuKey Laboratory of Microbiological Metrology, Measurement & Bio-product Quality Security, State Administration for Market Regulation, College of Life Science, China Jiliang University, Hangzhou 310018, China.
Xiaoping YuKey Laboratory of Microbiological Metrology, Measurement & Bio-product Quality Security, State Administration for Market Regulation, College of Life Science, China Jiliang University, Hangzhou 310018, China.
Zihong YeKey Laboratory of Microbiological Metrology, Measurement & Bio-product Quality Security, State Administration for Market Regulation, College of Life Science, China Jiliang University, Hangzhou 310018, China.
Haizhi HuangKey Laboratory of Microbiological Metrology, Measurement & Bio-product Quality Security, State Administration for Market Regulation, College of Life Science, China Jiliang University, Hangzhou 310018, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitrofurazone and its metabolite semicarbazide (SEM) residues present in food products pose substantial health hazards to humans. Herein, the colorimetric-fluorescent lateral flow immunoassay (LFIA) for 4[(4-carboxyphenyl)-methylene]-hydrazinecarboxamide (CPSEM) detection was developed using PCN-222@Pectin as a signal tag. Herein, the PCN-222 surface was subsequently modified with pectin to enhance its aqueous solubility and stability. The PCN-222@Pectin-LFIA system exhibited a broad linear range from 0.025 ng/mL to 100 ng/mL. The low limits of detection for the colorimetric and fluorescence-based detection methods were 0.1 and 0.05 ng/mL, respectively. Notably, these values represent a 10- and 20-fold higher sensitivity than that of the traditional colloidal gold nanoparticle-based LFIA. This method was successfully used to detect CPSEM in actual samples, with recovery rates of 89.34 %-120.80 %. This approach fulfills the need for on-site preliminary qualitative assessment during detection and permits subsequent accurate quantitative analysis.

Indexed as

Colorimetric-fluorescent immunoassay probeLateral flow immunoassayMetal-organic frameworksNitrofurazone

Identifiers

PMID41497702
PMCPMC12766102

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.