Evidence map›Paper›PMID 41497645›Full record

ArticlebioRxiv : the preprint server for biology2025

Pglyrp1-Cre Marks Distinct Epithelial and Immune Lineages Across Mucosal Sites.

Samuel Alvarez-Arguedas, Michael U Shiloh

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Samuel Alvarez-ArguedasDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.ORCID 0000-0002-5748-6078
Michael U ShilohDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.ORCID 0000-0003-4329-2253

Funding

Human airway microfold cells in mucosal immunity to bacterial pathogensU01AI125939 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI SHILOH, MICHAEL · 2016 to 2020
$2.2M
Interaction of Mycobacterium tuberculosis with upper airway mucosal cellsR01AI184584 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI MICHAEL SHILOH · 2024 to 2026
$2.2M
NIAID NIH HHS R01 AI184584NIAID NIH HHS U01 AI125939
6 · The paper itself

Abstract

Mucosa-associated lymphoid tissue (MALT) initiates immune responses at mucosal entry sites. Within MALT microfold (M) cells sample luminal antigens and deliver them to underlying immune cells. Despite their functional importance, few tools enable selective manipulation of M cells

Indexed as

M cellsMucosal immunityPglyrp1-Cre

Identifiers

PMID41497645
PMCPMC12767660

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.