Evidence map›Paper›PMID 41497632›Full record

ArticlebioRxiv : the preprint server for biology2025

PBX-dependent and independent Hox programs establish and maintain motor neuron terminal Identity.

Manasa Prahlad, Weidong Feng, Oyunsuvd Bat-Erdene, Yihan Chen, Paschalis Kratsios

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Manasa PrahladDepartment of Neurobiology, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-7849-9436
Weidong FengDepartment of Neurobiology, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-6642-1906
Oyunsuvd Bat-ErdeneDepartment of Neurobiology, University of Chicago, Chicago, IL 60637, USA.
Yihan ChenDepartment of Neurobiology, University of Chicago, Chicago, IL 60637, USA.ORCID 0009-0000-6095-2052
Paschalis KratsiosDepartment of Neurobiology, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-1363-9271

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Training Program in Developmental BiologyT32HD055164 · NICHD · UNIVERSITY OF CHICAGO · PI Sally Horne-Badovinac, Paschalis Kratsios · 2008 to 2026
$3.6M
Hox-dependent mechanisms for establishment and maintenance of motor neuron terminal identityR01NS116365 · NINDS · UNIVERSITY OF CHICAGO · PI KRATSIOS, PASCHALIS · 2020 to 2024
$2.0M
NICHD NIH HHS T32 HD055164NIH HHS P40 OD010440NINDS NIH HHS R01 NS116365
6 · The paper itself

Abstract

Motor neuron (MN) diversity is essential for producing the broad repertoire of animal movements, yet the molecular mechanisms that specify MN subtypes remain incompletely defined. Here, we investigate how Hox genes and their PBX cofactors shape cholinergic MN subtype identity along the anterior-posterior (A-P) axis of the

Identifiers

PMID41497632
PMCPMC12767569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.