Evidence map›Paper›PMID 41497610›Full record

ArticlebioRxiv : the preprint server for biology2026

Characterizing the Impact of Nucleoid-Associated Proteins on HU-DNA Interactions by Live-Cell Single-Molecule Tracking.

D E H Fuller, X Dai, L A McCarthy, L E Way, X Wang, J S Biteen

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

D E H FullerDepartment of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA.
X DaiDepartment of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA.ORCID 0000-0002-6190-392X
L A McCarthyDepartment of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA.ORCID 0000-0002-9646-5333
L E WayDepartment of Biology, Indiana University, Bloomington, IN, 47405, USA.ORCID 0000-0002-1491-2305
X WangDepartment of Biology, Indiana University, Bloomington, IN, 47405, USA.ORCID 0000-0001-6458-180X
J S BiteenDepartment of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA.ORCID 0000-0003-2038-6484

Funding

Michigan IRACDA: Training Future Professors of Engineering and PhysiologyK12GM111725 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROOKS, SUSAN V, SEPT, DAVID · 2016 to 2025
$7.9M
Physicochemical properties driving membraneless organelle assembly in bacteriaR01GM143182 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BITEEN, JULIE, MEYER, ANNE SARA · 2021 to 2024
$2.4M
Determining the molecular basis of gene silencing by MucR and defining its role in Brucella virulenceR01AI172822 · NIAID · EAST CAROLINA UNIVERSITY · PI ROY M ROOP · 2023 to 2026
$2.3M
How bacterial SMC complexes organize chromosomes (Equipment Supplement)R01GM141242 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI WANG, XINDAN · 2021 to 2025
$1.8M
Mapping the Interactions and Dynamics that Organize Bacteria CellsR01GM144731 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BITEEN, JULIE · 2022 to 2025
$1.2M
NIAID NIH HHS R01 AI172822NIGMS NIH HHS K12 GM111725NIGMS NIH HHS R01 GM141242NIGMS NIH HHS R01 GM143182NIGMS NIH HHS R01 GM144731
6 · The paper itself

Abstract

The bacterial nucleoid undergoes extensive structural reorganization during growth, influenced by nucleoid-associated proteins (NAPs) whose interactions and effects on nucleoid organization remain unclear. We investigated these interactions by tracking single molecules of the NAP HUα-PAmCherry in living

Identifiers

PMID41497610
PMCPMC12767515

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.