Evidence map›Paper›PMID 41497581›Full record

ArticlebioRxiv : the preprint server for biology2025

Circulating extracellular vesicle microRNAs mediate immune modulation of social behavior in mice.

Ken Matoba, Eisuke Dohi, Phoebe A Garcia, Jose Francis-Oliveira, Mirmohammadali Mirramezanializamini, Inssaf Berkiks, Frida Anguiano, Jana H Badrani, Oluwaseun Fatoba, Eric Y Choi and 12 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Ken Matoba
Eisuke Dohi
Phoebe A Garcia
Jose Francis-Oliveira
Mirmohammadali Mirramezanializamini
Inssaf Berkiks
Frida Anguiano
Jana H Badrani
Oluwaseun Fatoba
Eric Y Choi
Julia See
Md Sorwer Alam Parvez
Takahiro Kochi
Norimichi Ito
Rei Mitani
Indigo V L Rose
Takashi Imai
David K Crossman
Mikhail V Pletnikov
Kenneth W Witwer
Minae Niwa

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) are cell-derived small membrane vesicles and circulate throughout the body, but the impact of circulating EVs on brain function and behavior remains elusive. Here, we report that wild-type (WT) mouse blood, particularly EVs, increases sociability in socially impaired immunodeficient

Identifiers

PMID41497581
PMCPMC12767323

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.