ReviewJournal of tissue engineering and regenerative medicine2025
Collagen-Based Scaffolds for Meniscal Repair and Regeneration.
Review in Journal of tissue engineering and regenerative medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Embedded cell-only bioprinting to engineer structurally aligned meniscal fibrocartilage.Materials today. Bio · 2026Article
- Meniscus Tissue Engineering Scaffolds: Biomaterials, Biofabrication, and Translation.Polymers · 2026Review
- Self-assembled meniscus-specific ECM membrane promotes cell migration and vascular ingrowth for meniscus repair and reconstruction.Journal of orthopaedic translation · 2026Article
- Collagen-Based Scaffolds for Meniscal Repair and Regeneration.Journal of tissue engineering and regenerative medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Meniscal injuries present a significant clinical challenge due to the limited self-healing capacity of avascular regions and the unsatisfactory long-term outcomes of current repair strategies. Collagen, the primary structural component of the meniscal extracellular matrix (ECM), plays a crucial role in maintaining its biomechanical integrity and guiding tissue regeneration. This review summarizes recent advances in collagen scaffolds technology, focusing on materials, collagen extraction, and scaffold fabrication methods, as well as their in vivo interactions with cells that regulate tissue regeneration. The mechanical enhancement of collagen scaffolds through crosslinking and reinforcement with synthetic polymers is discussed, alongside strategies for controlled degradation and biological integration. Despite remaining challenges in mechanical durability and long-term stability, these developments position collagen-based scaffolds as a promising avenue toward clinically viable meniscal repair solutions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.