ReviewSynthetic and systems biotechnology2025
Engineered bacteriophage-based bioimaging Technology: Development and applications.
Review in Synthetic and systems biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Fluorescent Chemosensors as Precision Tools for Bioimaging and Environmental Monitoring: Advances, Challenges, and Future Directions.Journal of fluorescence · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Engineered bacteriophages (phages) have emerged as powerful and versatile tools for bioimaging, owing to their natural specificity for bacterial targets and their amenability to functional modification. This review summarizes recent advances in the development and application of phage-based imaging probes, with a particular focus on surface functionalization techniques and genetic engineering strategies used to construct functional phage imaging agents. These engineered phage probes have been applied across diverse imaging modalities, including fluorescence, magnetic resonance imaging (MRI), nuclear imaging, near-infrared (NIR) optical imaging, and surface-enhanced Raman scattering (SERS), etc. and have been utilized to enable highly sensitive detection of bacterial pathogens, improved diagnosis of infectious diseases, and monitoring of tissue engineering processes. Despite these innovations, critical challenges remain in ensuring robust target specificity, precise control of labeling stoichiometry, and favorable biocompatibility. Addressing issues such as non-specific probe binding, signal quenching, and immunogenicity will be crucial to fully realize the potential of phage-based bioimaging. Looking ahead, this review discusses future directions for next-generation phage imaging platforms with enhanced specificity, multiplexed functionality, and improved translational potential for clinical diagnostics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.