Evidence map›Paper›PMID 41497492›Full record

ArticleClinical psychological science : a journal of the Association for Psychological Science2025

A Framework for Estimating Posttreatment Moderation of Treatment-by-Dosage Effects in Individual-Patient Meta-Analysis: An Illustration Using Project Harmony.

Antonio A Morgan-López, Shannon M Blakey, Stephen G West, Skye Fitzpatrick, Sonya B Norman, Therese K Killeen, Sudie E Back, Lissette M Saavedra, Alexander C Kline, Teresa López-Castro and 1 more

Abstract read
In one paragraph

Article in Clinical psychological science : a journal of the Association for Psychological Science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Indirect Effects of the Coping Power Intervention on Latent Suicidal Thoughts and Behaviors: an Integrative Data Analysis.Prevention science : the official journal of the Society for Prevention Research · 2026
    Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Antonio A Morgan-LópezCenter for Behavioral Health and Wellbeing, RTI International, Research Triangle Park, North Carolina.ORCID 0000-0003-4706-9964
Shannon M BlakeyCenter for Behavioral Health and Wellbeing, RTI International, Research Triangle Park, North Carolina.ORCID 0000-0002-9291-3688
Stephen G WestDepartment of Psychology, Arizona State University.
Skye FitzpatrickDepartment of Psychology, York University.ORCID 0000-0002-1347-1827
Sonya B NormanDepartment of Psychiatry, University of California-San Diego.
Therese K KilleenDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina.
Sudie E BackDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina.
Lissette M SaavedraCenter for Behavioral Health and Wellbeing, RTI International, Research Triangle Park, North Carolina.
Alexander C KlineDepartment of Psychiatry, University of California-San Diego.ORCID 0000-0001-7420-7547
Teresa López-CastroDepartment of Psychology, City College of New York.ORCID 0000-0003-2521-6329
Denise A HienCenter of Alcohol & Substance Use Studies, Rutgers University-New Brunswick.ORCID 0000-0002-6954-2882

Funding

Meta-analysis of Individual Patient Data for PTSD/AODsR01AA025853 · NIAAA · RESEARCH TRIANGLE INSTITUTE · PI HIEN, DENISE AIMEE, MORGAN-LOPEZ, ANTONIO A · 2018 to 2021
$1.7M
NIAAA NIH HHS R01 AA025853
6 · The paper itself

Abstract

Making causal statements regarding dose-response in treatments for posttraumatic stress disorder (PTSD) and alcohol/other drug use disorders (AODs; PTSD+AOD) is difficult because (a) dosage is rarely randomized and (b) self-selected dosage can be affected by treatment assignment. In the present study, we sought to clarify causal inferences regarding treatment-by-dosage interactions in PTSD+AOD treatment using Project Harmony, an individual-patient meta-analytic data set of behavioral, pharmacological, and combination PTSD+AOD treatments (

Indexed as

dose-responsemeta-analysisPTSDsubstance use

Identifiers

PMID41497492
PMCPMC12768495

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.