Evidence map›Paper›PMID 41497484›Full record

ArticleJournal of diabetes research2025

Correlation of Serum Growth Differentiation Factor 15 With Metabolic Syndrome and Its Components in Patients With Type 2 Diabetes Mellitus.

Yiran Zhao, Yonghong Cao, Yue Li, Xinxiu Zhang, Wu Dai, Jiajia Song, Dechao Yin, Xiaofang Han

Abstract read
In one paragraph

Article in Journal of diabetes research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yiran ZhaoDepartment of Endocrinology, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, China, ahmu.edu.cn.ORCID https://orcid.org/0009-0004-5385-3055
Yonghong CaoDepartment of Endocrinology, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, China, ahmu.edu.cn.ORCID https://orcid.org/0000-0002-5433-4212
Yue LiDepartment of Endocrinology, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, China, ahmu.edu.cn.ORCID https://orcid.org/0009-0002-8012-8137
Xinxiu ZhangDepartment of Endocrinology, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, China, ahmu.edu.cn.
Wu DaiDepartment of Endocrinology, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, China, ahmu.edu.cn.
Jiajia SongDepartment of Endocrinology, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, China, ahmu.edu.cn.ORCID https://orcid.org/0000-0001-7128-343X
Dechao YinDepartment of Endocrinology, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, China, ahmu.edu.cn.
Xiaofang HanDepartment of Endocrinology, The Second People's Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, China, ahmu.edu.cn.ORCID https://orcid.org/0000-0002-2136-6621

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The purpose of this study is to explore the association between serum growth differentiation factor 15 (GDF15) and metabolic syndrome (MS), as well as its components in patients with Type 2 diabetes mellitus (T2DM). Patients and Methods: Data on 125 patients with T2DM admitted to the Department of Endocrinology of the Second People's Hospital of Hefei City between August 2022 and June 2023 were retrospectively collected. According to the diagnostic criteria of MS, the patients were divided into two groups: T2DM alone (67 cases) and T2DM combined with MS (58 cases). General conditions and laboratory indicators of the patients were collected to analyze the correlation of GDF15 expression in T2DM and combined MS. Results: The GDF15 level in the T2DM with MS group was higher than that in the T2DM group ( Conclusion: Serum GDF15 is strongly correlated with T2DM combined with MS and its components, and elevated GDF15 is valuable for the diagnosis of T2DM combined with MS.

Indexed as

Diabetes Mellitus, Type 2Growth Differentiation Factor 15Metabolic SyndromeAdultBiomarkersFemaleHumansMaleMiddle AgedRetrospective StudiesBiomarkersGDF15 protein, humanGrowth Differentiation Factor 15growth differentiation factor 15metabolic syndromeobesityType 2 diabetes mellitus

Identifiers

PMID41497484
PMCPMC12767226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.