Evidence map›Paper›PMID 41497363›Full record

ArticleSSM - health systems2025

A formative evaluation of potential barriers and facilitators to inform effective implementation of a community-based hypertension care program in rural South Africa: The IMPACT-BP trial.

Shafika Abrahams-Gessel, Thabang Manyaapelo, Nsika Sithole, Siphephelo Dlamini, Nondumiso Mpanza, Samukelisiwe Nxumalo, Thabisile Mjilo, Joanna Orne-Gliemann, Max Bachmann, Nombulelo Magula and 3 more

Abstract read
In one paragraph

Article in SSM - health systems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Home-Based Care for Hypertension in Rural South Africa.The New England journal of medicine · 2025
    Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shafika Abrahams-GesselHarvard TH Chan School of Public Health, Center for Health Decision Science, 718 Huntington Avenue, Boston, MA 02115, United States.ORCID 0000-0003-4954-057X
Thabang ManyaapeloAfrica Health Research Institute, 719 Umbilo Road, Durban, R618 to Hlabisa, Somkhele, KwaZulu-Natal, South Africa.
Nsika SitholeAfrica Health Research Institute, 719 Umbilo Road, Durban, R618 to Hlabisa, Somkhele, KwaZulu-Natal, South Africa.
Siphephelo DlaminiKwazulu-Natal Province, Department of Health, D850 Road, Msiyane Area, Jozini, KwaZulu-Natal 3969, South Africa.
Nondumiso MpanzaAfrica Health Research Institute, 719 Umbilo Road, Durban, R618 to Hlabisa, Somkhele, KwaZulu-Natal, South Africa.
Samukelisiwe NxumaloAfrica Health Research Institute, 719 Umbilo Road, Durban, R618 to Hlabisa, Somkhele, KwaZulu-Natal, South Africa.
Thabisile MjiloAfrica Health Research Institute, 719 Umbilo Road, Durban, R618 to Hlabisa, Somkhele, KwaZulu-Natal, South Africa.
Joanna Orne-GliemannUniversity of Bordeaux, National Institute for Health and Medical Research (INSERM) UMR 1219, Research Institute for Sustainable Development (IRD) EMR 271, Bordeaux Population Health Centre, Bordeaux, France.
Max BachmannNorwich Medical School, University of East Anglia, Norwich NR47TJ, United Kingdom.
Nombulelo MagulaDivision of Internal Medicine, University of KwaZulu-Natal, Medical School, Private Bag 7, Congella, Durban, KwaZulu-Natal 4013, South Africa.
Alison CastleAfrica Health Research Institute, 719 Umbilo Road, Durban, R618 to Hlabisa, Somkhele, KwaZulu-Natal, South Africa.
Mark J SiednerAfrica Health Research Institute, 719 Umbilo Road, Durban, R618 to Hlabisa, Somkhele, KwaZulu-Natal, South Africa.
Thomas GazianoHarvard TH Chan School of Public Health, Center for Health Decision Science, 718 Huntington Avenue, Boston, MA 02115, United States.

Funding

Partnership for Global Health Research Training Program (Renewal)-Supplement for OBSSR, NCI, NCI-AIDS and NIDCDD43TW010543 · FIC · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Wafaie W Fawzi, DAVIDSON HOWES HAMER · 2017 to 2026
$12.1M
PROGRAM FOR AIDS CLINICAL RESEARCH TRAINING (PACRT)T32AI007433 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MARK J SIEDNER · 1992 to 2026
$11.4M
Implementation of a Combination Intervention for Sustainable Blood Pressure Control in Rural KwaZulu-Natal, South Africa (IMPACT-BP)R01HL144848 · NHLBI · KWAZULU-NATAL RESEARCH INSTITUTE TB-HIV · PI GAZIANO, THOMAS A, SIEDNER, MARK J · 2020 to 2024
$2.9M
Mentoring patient-oriented research to improve cardiovascular health among people with HIV in sub-Saharan AfricaK24HL166024 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MARK J SIEDNER · 2022 to 2026
$616k
Engaging men outside the HIV prevention paradigm in rural South AfricaK23MH136873 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI Alison Clare Castle · 2025 to 2026
$392k
FIC NIH HHS D43 TW010543NHLBI NIH HHS K24 HL166024NHLBI NIH HHS R01 HL144848NIAID NIH HHS T32 AI007433NIMH NIH HHS K23 MH136873Wellcome Trust
6 · The paper itself

Abstract

Background: In rural KwaZulu-Natal Province, South Africa, less than 25 % of persons with hypertension have controlled blood pressure. We conducted a formative evaluation of current clinic-based care to identify barriers and facilitators that could impact effective implementation of a community-based hypertension intervention (IMPACT-BP). Methods: We conducted individual interviews and group discussions with clinic managers, nurses, community health workers (CHWs), community leaders, and patients to identify barriers and facilitators experienced in clinic-based hypertension care, which could affect the acceptability, feasibility, and implementation of the IMPACT-BP intervention. The Conceptual Model of Implementation Research and the Theoretical Framework of Acceptability guided the design of data collection instruments and analysis. Qualitative data collection was performed by trained social science research assistants, recorded, transcribed, translated, and analyzed using thematic analysis. Results: Forty-one participants (92 % women) participated in group discussions (n = 32) or individual interviews (n = 9). Barriers to intervention acceptability and feasibility included inadequate levels of staffing, high patient volumes, distrust of CHWs' work at clinics and in the community, and insufficient training and equipment for CHWs. Facilitators included home delivery of medications by CHWs. Conclusions: Our findings allowed us to identify specific adaptations to the intervention implementation strategy to make the proposed community-based intervention acceptable and feasible in this setting. Adaptations included employing dedicated CHWs and nurses for trial-related activities, developing an expanded CHW training module on hypertension knowledge, teaching CHWs to measure blood pressure and subsequently train patients to do the same, and training CHWs to educate patients about hypertension management.

Indexed as

Community-basedCommunity health worker (CHW)Decentralized primary careFormativeHypertensionManagementRural South AfricaSelf-monitoringTask-sharing

Identifiers

PMID41497363
PMCPMC12768497

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.