ReviewChemical science2026
Liquid-liquid phase separation of peptides: a molecular foundation for next-generation biomaterials.
Review in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A pH-Responsive fluorescence lifetime probe reveals GOT1 phase separation in cellular anti-senescence.Smart molecules : open access · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Liquid-liquid phase separation (LLPS) is a key mechanism for organizing membraneless cellular compartments, influencing processes like stress response, signaling, and gene regulation. While intrinsically disordered proteins (IDPs) and their regions (IDRs) drive LLPS through weak, multivalent interactions, the complexity of full-length proteins limits systematic design and understanding of phase separation. Peptides, as simpler modular units, offer precise control over sequence composition and provide a scalable platform for studying LLPS. Recent advancements demonstrate that peptide condensates reveal fundamental phase separation rules and enable applications such as artificial cells and drug delivery systems. This perspective highlights recent progress in peptide LLPS, focusing on sequence design, structural characterization, and emerging applications, and discusses challenges and future directions for broader applications.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.