Evidence map›Paper›PMID 41497168›Full record

ArticleResearch and reports in urology2025

Unmasking Elevated PSA: Prevalence and Modifiable Risk Factors in Men Aged ≥ 40 Years Attending Kabutare District Hospital in Rwanda.

Erneste Mugenzi, Jean Paul Dusengimana, Danny Habumugisha, Happy Jean Bosco Asifiwe, Anathalie Umuhoza, Diogene Rwayitare, Tiruzer Bekele, Schifra Uwamungu, Augustin Nzitakera, Cuthbert Musarurwa

Abstract read
In one paragraph

Article in Research and reports in urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Erneste MugenziDepartment of Biomedical Laboratory Sciences, School of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Jean Paul DusengimanaDepartment of Biomedical Laboratory Sciences, School of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Danny HabumugishaDepartment of Biomedical Laboratory Sciences, School of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Happy Jean Bosco AsifiweDepartment of Biomedical Laboratory Sciences, School of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.ORCID 0009-0001-0738-8437
Anathalie UmuhozaDepartment of Biomedical Laboratory Sciences, School of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Diogene RwayitareDepartment of Biomedical Laboratory Sciences, School of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Tiruzer BekeleDepartment of Biomedical Laboratory Sciences, School of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Schifra UwamunguDepartment of Biomedical Laboratory Sciences, School of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Augustin NzitakeraDepartment of Biomedical Laboratory Sciences, School of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.ORCID 0000-0002-7871-3954
Cuthbert MusarurwaDepartment of Biomedical Laboratory Sciences, School of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.ORCID 0000-0001-8248-427X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of the study was to determine the prevalence of elevated PSA levels (> 4.0 ng/mL) and examine sociodemographic and modifiable lifestyle risk factors associated with PSA elevation among asymptomatic Rwandan men aged ≥ 40 years. Material and Methods: A cross-sectional study was conducted at Kabutare District Hospital in Rwanda between March and April 2025, enrolling 136 asymptomatic male participants aged ≥ 40 years. Lifestyle and anthropometric data were collected via structured interviews. Serum total PSA was measured using the enzyme linked immunosorbent assay (Fortress BXE0851A kit). Elevated PSA was defined as > 4.0 ng/mL. Statistical analyses included descriptive statistics and Chi-square/Fisher's exact tests for bivariate associations. Results: Elevated PSA was observed in 14% of participants. Chi-square analysis revealed significant associations between elevated PSA and BMI category ( Conclusion: Elevated PSA prevalence among asymptomatic Rwandan men mirrors global patterns observed in Black populations. Associations with underweight status, occupational exposure, and alcohol use suggest multifactorial influences. These findings highlight the need for targeted screening strategies and community-level interventions to promote early prostate cancer detection in Rwanda.

Indexed as

ELISAmodifiable risk factorsoccupational exposureprostate cancerPSARwandascreening

Identifiers

PMID41497168
PMCPMC12765937

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.