Evidence map›Paper›PMID 41496978›Full record

ArticleAnnals of medicine and surgery (2012)2026

4D-Morphing biopolymers in reconstructive plastic surgery: implications, challenges and a call for clinical-translation.

Asra Amjad, Maryam Waqar, Umair Ali, Raghabendra Kumar Mahato

Abstract readLetter
In one paragraph

Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Asra AmjadDepartment of Medicine, Islamic International Medical College, Riphah International University, Rawalpindi, Pakistan.
Maryam WaqarDepartment of Medicine, Dow Medical College, Karachi, Pakistan.
Umair AliDepartment of Pharmacy, University of Swabi, Pakistan.
Raghabendra Kumar MahatoDepartment of Medicine, Gandaki Medical College Teaching Hospital and Research Center, Pokhara, Nepal.ORCID https://orcid.org/0009-0009-9434-1650

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The concept behind 4D morphing biopolymers represents a further improvement in reconstructive plastic surgery, as it can now create scaffolds that are stimulus-responsive, allowing them to exhibit flexibility in shape and functionality once implanted. Such materials have the potential to address the shortcomings of conventional autologous reconstruction through enhanced integration, vascularization, and minimally invasive implantation. Nevertheless, significant issues of translation, regulation, and ethics remain, underscoring the need for in vivo research, surgeon-engineer partnerships, and fair clinical practice.

Indexed as

4D biopolymersreconstructionscaffoldsshape-memorytranslation

Identifiers

PMID41496978
PMCPMC12768201

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.