Evidence map›Paper›PMID 41496934›Full record

ArticleAnnals of medicine and surgery (2012)2026

Nanoparticle-enhanced CRISPR delivery: paving the path for

Muhammad Khizar, Hasibullah Aminpoor, Muhammad Zaib, Qaima Ali, Hasiba Karimi

Abstract readLetter
In one paragraph

Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammad KhizarFaculty of Medicine, Georgian American University, Manifest Medical Research Co, Tbilisi, Georgia.ORCID https://orcid.org/0009-0005-5229-5052
Hasibullah AminpoorFaculty of Medicine, Kabul University of Medical Sciences "Abu Ali Ibn Sina", Kabul, Afghanistan.ORCID https://orcid.org/0000-0003-1817-7800
Muhammad ZaibFaculty of Medicine, Georgian American University, Manifest Medical Research Co, Tbilisi, Georgia.ORCID https://orcid.org/0009-0008-7675-7161
Qaima AliFaculty of Medicine, Liaquat College of Medicine & Dentistry, Karachi, Pakistan.ORCID https://orcid.org/0009-0002-4771-9955
Hasiba KarimiFaculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.ORCID https://orcid.org/0000-0002-7618-3849

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticle-based delivery systems are redefining how CRISPR/Cas technology can be used in cancer treatment. By encapsulating CRISPR components within lipid, polymeric, or inorganic nanoparticles, researchers have improved their stability, circulation time, and tumor-targeting precision. The NTLA-2001 trial demonstrated the first successful use of lipid nanoparticles for

Indexed as

cancer therapyCRISPR Cas9in vivo gene editinglipid nanoparticlesnanoparticle deliveryprecision oncology

Identifiers

PMID41496934
PMCPMC12768121

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.