Evidence map›Paper›PMID 41496832›Full record

ArticleRSC advances2026

Influence of intramolecular interactions and transition state energetics on the strain-promoted azide-alkyne cycloaddition of 2-aminobenzenesulfonamide-containing cyclononynes.

Kazuhide Nakahara, Kyosuke Kaneda

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kazuhide NakaharaHokkaido University of Science, Faculty of Pharmaceutical Sciences 15-4-1, Maeda 7-jo Teine-ku Sapporo-shi Hokkaido 006-8585 Japan nakahara-k@hus.ac.jp.ORCID https://orcid.org/0000-0003-1553-7989
Kyosuke KanedaHokkaido University of Science, Faculty of Pharmaceutical Sciences 15-4-1, Maeda 7-jo Teine-ku Sapporo-shi Hokkaido 006-8585 Japan nakahara-k@hus.ac.jp.ORCID https://orcid.org/0000-0003-2415-2685

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Computational investigation of the reaction mechanism and selectivity of strain-promoted azide-alkyne cycloaddition indicated that 2-aminobenzenesulfonamide-containing cyclononyne (ABSACN) is a HOMO donor; the energy difference is slight between the transition states (TSs) for the major and minor products. The reaction between unsubstituted ABSACN(R

Identifiers

PMID41496832
PMCPMC12766270

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.