ArticleExperimental and therapeutic medicine2026
Association of thrombocytopenia with deep vein thrombosis in patients with acute exacerbations of chronic obstructive pulmonary disease: A retrospective study.
Article in Experimental and therapeutic medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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8 authors.
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Abstract
Acute exacerbations of chronic obstructive pulmonary disease (AE-COPD) are often accompanied by systemic inflammatory responses and can lead to coagulation disorders and thrombotic complications, thereby increasing hospitalization rates and mortality. Platelets play a critical role not only in hemostasis and thrombosis, but also in immunity and inflammation. The aim of the present study was to explore the associations among thrombocytopenia, infection severity and deep vein thrombosis (DVT) formation in patients with AE-COPD, and to develop a predictive model based on platelet-related parameters. The clinical data from 338 patients with AE-COPD who were hospitalized in the Department of Respiratory and Critical Care Medicine of The Affiliated Jiangning Hospital of Nanjing Medical University (Nanjing, China) between January 2021 and December 2023 were retrospectively evaluated. Demographic characteristics, medical history, comorbidities, laboratory test results, lower limb venous ultrasound findings, chest computed tomography scans and mechanical ventilation treatment data were collected. Statistical analyses were performed using SPSS version 26.0, GraphPad Prism version 9.0 and R version 4.1.3. Among the 338 patients with AE-COPD, 72.4% were male and the mean age was 75.60±7.42 years. The thrombocytopenia group (<150x10
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