Evidence map›Paper›PMID 41496797›Full record

ArticleJournal of pain research2025

Moving Beyond One-Size-Fits-All: Charting a Path to Personalized Nonpharmacological and Noninvasive Chronic Pain Management.

Qiang Xie, Simon B Goldberg, Nora Jacobson, David Rakel, Andrew Quanbeck

Abstract read
In one paragraph

Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qiang XieDepartment of Family Medicine and Community Health, University of Wisconsin - Madison, Madison, WI, USA.ORCID 0000-0003-3968-9629
Simon B GoldbergDepartment of Counseling Psychology, University of Wisconsin - Madison, Madison, WI, USA.ORCID 0000-0002-6888-0126
Nora JacobsonInstitute for Clinical and Translational Research, University of Wisconsin - Madison, Madison, WI, USA.ORCID 0000-0002-5118-8475
David RakelDepartment of Family Medicine and Community Health, University of Wisconsin - Madison, Madison, WI, USA.
Andrew QuanbeckDepartment of Family Medicine and Community Health, University of Wisconsin - Madison, Madison, WI, USA.ORCID 0000-0003-0762-4804

Funding

Promoting the implementation of clinical guidelines for opioid prescribing in primary care using systems consultationR01DA047279 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI QUANBECK, ANDREW · 2018 to 2022
$3.5M
Integrating mHealth for Alcohol Use Disorders into Clinical PracticeR01AA024150 · NIAAA · UNIVERSITY OF WISCONSIN-MADISON · PI QUANBECK, ANDREW · 2018 to 2022
$3.3M
Advancing Resources for Systematic Reviews and Meta-Analyses of Complementary and Integrative Health InterventionsR24AT012845 · NCCIH · BROWN UNIVERSITY · PI Simon B Goldberg, Eric Loucks · 2024 to 2026
$1.8M
Mindfulness training delivered via mobile health to reduce depression and anxietyK23AT010879 · NCCIH · UNIVERSITY OF WISCONSIN-MADISON · PI GOLDBERG, SIMON B · 2020 to 2024
$786k
NCCIH NIH HHS K23 AT010879NCCIH NIH HHS R24 AT012845NIAAA NIH HHS R01 AA024150NIDA NIH HHS R01 DA047279
6 · The paper itself

Abstract

One-size-fits-all opioid treatment for chronic pain may undermine treatment effectiveness and cause adverse effects. We explore personalized nonpharmacological and noninvasive chronic pain treatment as a promising approach to minimize these risks and optimize outcomes for each patient. Our paper introduces the definition of personalized treatment, emphasizes the significance of intervention personalization, and outlines strategies for inter- and intra-patient personalization in chronic pain management. We also discuss empirical studies on personalized chronic pain treatment. Research has shown a variety of strategies for personalizing nonpharmacological and noninvasive chronic pain treatment. These strategies have demonstrated the potential to improve effectiveness. However, many critical scientific questions remain unanswered. To fully harness the potential of personalized nonpharmacological and noninvasive chronic pain treatment, future research should conduct robust clinical trials and meta-analyses comparing personalized and non-personalized chronic pain interventions, examine diverse personalization approaches, incorporate ecological momentary assessment into outcomes assessment, leverage digital technologies, engage patients in treatment design, and assess factors influencing the implementation of personalized chronic pain treatment.

Indexed as

chronic painpersistent painpersonalized interventionpersonalized medicineprecision medicine

Identifiers

PMID41496797
PMCPMC12765933

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.