ArticlePain research & management2025
Prevalence and Predictors of Severity of Rebound Pain After Regional Anesthesia in Patients Undergoing Orthopedic Surgery: A Cross-Sectional Study.
Article in Pain research & management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Rebound pain following peripheral nerve block in extremity fracture surgery: pathophysiological mechanisms based on the "Triple-Hit" model and multimodal preventive strategies.Frontiers in medicine · 2026Review
- Prevalence and Predictors of Severity of Rebound Pain After Regional Anesthesia in Patients Undergoing Orthopedic Surgery: A Cross-Sectional Study.Pain research & management · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Rebound pain (RP) is an acute, burning, or dull-aching type of pain that occurs following the resolution of regional anesthesia. It is a common but understudied problem in orthopedic patients undergoing surgery under regional anesthesia. This study aimed to determine the prevalence and predictors of RP severity in patients undergoing orthopedic surgeries. Methods: A cross-sectional study was conducted involving 364 patients who underwent orthopedic surgery and received regional anesthesia. To determine factors associated with the severity of RP, bivariable and multivariable ordinal logistic regression analyses were conducted. Both crude and adjusted odds ratios with their corresponding 95% confidence interval were calculated to determine the strength of association. Result: The prevalence of RP after resolution of regional anesthesia was 70.9% (95% CI: 65.9-75.5). Among all participants, 30.2% experienced mild RP, 19.2% had moderate pain, and 21.4% reported severe RP. Age less than 60 years (AOR: 2.34, 95% CI: 1.38-3.95, and Conclusion: Our study found a high incidence of RP following the resolution of regional anesthesia in patients undergoing orthopedic surgery. To reduce its incidence and severity, it is essential to effectively manage and alleviate preoperative pain, incorporate local anesthetic adjuvants into nerve block solutions, utilize intravenous dexamethasone, and incorporate multimodal analgesia before the resolution of regional anesthesia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.