Evidence map›Paper›PMID 41496762›Full record

ArticleJournal of adult development2025

From Adversity to Purpose: How Self-Compassion and Age Influence Meaning in Life Among Adults with Adverse Childhood Experiences.

Miya M Gentry, Deepa Manjanatha, Molly A Patapoff, Barton W Palmer

Abstract read
In one paragraph

Article in Journal of adult development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Miya M GentrySan Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, USA.ORCID 0000-0002-5925-0413
Deepa ManjanathaSan Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, USA.ORCID 0000-0002-4916-2153
Molly A PatapoffDepartment of Psychiatry, University of California San Diego, La Jolla, USA.ORCID 0000-0002-4152-9504
Barton W PalmerDepartment of Psychiatry, University of California San Diego, La Jolla, USA.ORCID 0000-0002-7618-3144

Funding

FELLOWSHIP IN GERIATRIC MENTAL HEALTHT32MH019934 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Elizabeth W Twamley · 1994 to 2026
$9.5M
NIMH NIH HHS T32 MH019934
6 · The paper itself

Abstract

Adverse childhood experiences (ACEs) are linked to negative health outcomes across the lifespan but less is known about psychological resources that might mitigate these effects. Meaning in life, conceptualized as presence (i.e., a sense of purpose and coherence) and search (i.e., striving for meaning), and self-compassion may serve as resilience factors that buffer the long-term impact of early adversity. The present study examined associations among ACEs, self-compassion, age, and meaning in life, testing whether self-compassion and age moderated the effects of ACEs. Participants were 875 community-dwelling adults (M = 66.1, SD = 20.8). Multiple linear regression models tested main and interaction effects of age and self-compassion on outcomes of presence of and search for meaning in life. Results indicated that self-compassion was a robust positive predictor of presence of meaning and a negative predictor in search for meaning. ACEs predicted lower presence of meaning, and both self-compassion and age moderated this relationship, such that adverse effects of ACEs were attenuated among individuals higher in self-compassion and among older adults. For search, self-compassion predicted lower search for meaning, while ACEs and the moderation effect was not statistically significant. These findings underscore the importance of distinguishing presence and search as distinct constructs and highlights the protective role of psychological and developmental resources in meaning-making following adversity. Self-compassion may represent a promising target for interventions aimed at fostering resilience in individuals with ACEs.

Indexed as

adverse childhood experienceslifespan developmentmeaning in liferesilienceself-compassion

Identifiers

PMID41496762
PMCPMC12768510

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.