Evidence map›Paper›PMID 41496190›Full record

ArticleComprehensive psychiatry2026

Responses to social defeat in early- vs late-onset suicidal behavior: An experimental behavioral study.

Anna Szücs, Elizabeth Campbell, Katalin Szanto, Alexandre Y Dombrovski

Abstract read
In one paragraph

Article in Comprehensive psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Anna SzücsFaculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Netherlands. Electronic address: a.szuecs@vu.nl.
Elizabeth CampbellDepartment of Psychiatry, University of Pittsburgh, USA.
Katalin SzantoDepartment of Psychiatry, University of Pittsburgh, USA.
Alexandre Y DombrovskiDepartment of Psychiatry, University of Pittsburgh, USA.

Funding

PSYCHOBIOLOGY OF SUICIDAL BEHAVIOR IN BPDR01MH048463 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Alexandre Y. Dombrovski · 1992 to 2026
$13.9M
Short Term Variability in Affect and Rest Activity Rhythms in Long Term Chronic and Highly Variable Suicidal Ideation in Depressed Older AdultsR01MH085651 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HANGA CSILLA GALFALVY, Swathi Gujral · 2010 to 2026
$9.6M
Reward Learning in Late-Life Suicidal BehaviorR01MH100095 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Alexandre Y. Dombrovski · 2014 to 2026
$6.8M
NIMH NIH HHS R01 MH048463NIMH NIH HHS R01 MH085651NIMH NIH HHS R01 MH100095
6 · The paper itself

Abstract

backgroundSocial defeat is often cited as a motive for suicide. The experience of defeat may arise from feeling dominated in a dyadic conflict or from losing status in a group. We hypothesize that sensitivity to dyadic defeat will be related to the onset of suicidal behavior in early or mid-life and sensitivity to loss of status, in late life.

methodsThe study's sample of 245 adults aged 50 years and older (mean = 63.2 years, SD = 7.4) comprised 42 early-onset and 32 late-onset suicide attempters (aged < 50 vs ≥ 50 years at their first suicide attempt), 114 depressed non-attempter comparisons, and 57 non-psychiatric comparisons. Using a validated rigged video game tournament task, we operationalized compensatory responses to the two forms of social defeat as point stealing from individual opponents (one-on-one defeat) and rank buying in the league table (loss of status in a group).

resultsEarly-onset attempters increased point stealing the most over time (χ

conclusionsOur behavioral findings suggest that socio-behavioral processes leading to suicide vary across the life cycle. While vulnerability to dyadic defeat could be suicidogenic for people of any age, loss of social status could play a role in suicidal crises specifically occurring in later life.

Indexed as

Social DefeatSuicide, AttemptedAgedAge of OnsetFemaleHumansMaleMiddle Agedcompetitiondefeatinterpersonal conflictloss of statusnarcissismold agesocial interactionssuicide

Identifiers

PMID41496190
PMCPMC13339945

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.