Evidence map›Paper›PMID 41495746›Full record

ArticleJournal of nanobiotechnology2026

Bacteria-powered LA@CaDGP biomotor: a multi-modal weapon integrating calcium overload, chemotherapy, and starvation for breast cancer therapy.

Jingrong Huang, Yongcheng Tang, Kewei Xiang, Biqiong Wang, Jia Wang, Yun Lu, Yue Li, Hongjun Deng, Tao Li, Kang Xiong and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jingrong Huang *Department of Oncology, The Affiliated Hospital, Southwest Medical University, Luzhou, 646000, Sichuan, PR China.
Yongcheng Tang *Department of General Surgery (Hepatopancreatobiliary Surgery), The Affiliated Hospital, Southwest Medical University, Luzhou, 646000, Sichuan, PR China.
Kewei Xiang *Department of Oncology, The Affiliated Hospital, Southwest Medical University, Luzhou, 646000, Sichuan, PR China.
Biqiong WangDepartment of Oncology, The Affiliated Hospital, Southwest Medical University, Luzhou, 646000, Sichuan, PR China.
Jia WangDepartment of Oncology, The Affiliated Hospital, Southwest Medical University, Luzhou, 646000, Sichuan, PR China.
Yun LuDepartment of Oncology, The Affiliated Hospital, Southwest Medical University, Luzhou, 646000, Sichuan, PR China.
Yue LiMedicine and health Klinikum rechts der Isar, Technical University of Munich, Ismaningerstr. 22, 81675, München, Germany.
Hongjun DengDepartment of Oncology, The Affiliated Hospital, Southwest Medical University, Luzhou, 646000, Sichuan, PR China.
Tao LiDepartment of Oncology, The Affiliated Hospital, Southwest Medical University, Luzhou, 646000, Sichuan, PR China.
Kang XiongDepartment of Oncology, The Affiliated Hospital, Southwest Medical University, Luzhou, 646000, Sichuan, PR China.
Qinglian WenDepartment of Radiation Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, PR China. wql73115@163.com.
Shaozhi FuDepartment of Oncology, The Affiliated Hospital, Southwest Medical University, Luzhou, 646000, Sichuan, PR China. shaozhifu513@163.com.

Funding

the Science and Technology Department of Sichuan Province 2025ZNSFSC0679
6 · The paper itself

Abstract

Chemotherapy remains a cornerstone in breast cancer treatment, but poor drug targeting compromises its efficacy and exacerbates side effects. To optimize drug delivery, we developed a novel bacteria-propelled biomotor system, designated as LA@CaDGP, to enhance the tumor-specific drug delivery. The biomotor was engineered to load doxorubicin (DOX) and glucose oxidase (GOD) within mesoporous calcium carbonate nanoparticles (CaCO

Indexed as

Antineoplastic AgentsBreast NeoplasmsCalciumCalcium CarbonateDoxorubicinAnimalsCell Line, TumorDrug Delivery SystemsFemaleGlucose OxidaseHumansIndolesMiceMice, Inbred BALB CNanoparticlesPolymersAntineoplastic AgentsCalciumCalcium CarbonateDoxorubicinGlucose OxidaseIndolespolydopaminePolymersBreast cancerCalcium carbonate nanoparticlesDoxorubicinGlucose oxidaseLactobacillus acidophilusStarvation therapy

Identifiers

PMID41495746
PMCPMC12870040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.