Evidence map›Paper›PMID 41495745›Full record

ArticleCost effectiveness and resource allocation : C/E2026

A digital diagnostic pathway for heart failure: an economic evaluation.

Nicola Mcmeekin, Andrew Davies, Mark C Petrie, Ross T Campbell, David J Lowe, Clare L Murphy, Leeanne Macklin, Katriona Brooksbank, Olivia Wu

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In one paragraph

Article in Cost effectiveness and resource allocation : C/E, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nicola McmeekinHealth Economics and Health Technology Assessment (HEHTA), University of Glasgow, Glasgow, UK. Nicola.mcmeekin@glasgow.ac.uk.
Andrew DaviesHealth Economics and Health Technology Assessment (HEHTA), University of Glasgow, Glasgow, UK.
Mark C PetrieSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Ross T CampbellSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
David J LoweQueen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, Glasgow, UK.
Clare L MurphyForth Valley Royal Hospital, NHS Forth Valley, Glasgow, UK.
Leeanne MacklinForth Valley Royal Hospital, NHS Forth Valley, Glasgow, UK.
Katriona BrooksbankSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Olivia WuHealth Economics and Health Technology Assessment (HEHTA), University of Glasgow, Glasgow, UK.

Funding

AstraZeneca Unrestricted grant
6 · The paper itself

Abstract

Guidelines recommend prompt diagnosis of suspected heart failure in people with elevated N-terminal pro b-type natriuretic peptide (NT-proBNP). Early diagnosis of heart failure improves patient outcomes, however diagnosis is complex and can often be delayed. Digital platforms can provide clinicians with greater access to information with which to diagnose heart failure, improving on standard diagnostic pathways. We modelled the potential cost-effectiveness of a digital pathway, adapting the UK NICE guideline (NG106) cost-effectiveness model to evaluate the impact of potentially speedier diagnosis and treatment of heart failure. Posited reductions in time to treatment were modelled to reduce short-term mortality and generate approximately 0.056 incremental quality adjusted life-years over a lifetime horizon. Additional costs arose from earlier heart failure treatment, resulting in a cost per quality adjusted life-year of £5,882 (95% confidence interval £4,377 - £11,084).

Indexed as

Cost-consequence analysisCost-effectivenessDiagnostic pathwaysEconomic evaluationHeart failureHeart failure diagnosis

Identifiers

PMID41495745
PMCPMC12870240

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.