Evidence map›Paper›PMID 41495638›Full record

ArticleBMC microbiology2026

Antimicrobial effects of Bacillus safensis BS05 cell free supernatant against Campylobacter jejuni and its probiotic evaluation.

Xuesong Zhang, Su Bian, Jikai Ren, Qian Gao, Yuanyue Tang, Fangzhe Ren, Xinan Jiao, Jinlin Huang

Abstract read
In one paragraph

Article in BMC microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xuesong ZhangJiangsu Key Lab of Zoonosis/Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, 48 Wenhui East Road, Yangzhou, Jiangsu, 225000, China.
Su BianKey Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agri-food Safety and Quality, Ministry of Agriculture of China, Yangzhou University, 48 Wenhui East Road, Yangzhou, Jiangsu, 225000, China.
Jikai RenKey Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agri-food Safety and Quality, Ministry of Agriculture of China, Yangzhou University, 48 Wenhui East Road, Yangzhou, Jiangsu, 225000, China.
Qian GaoKey Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agri-food Safety and Quality, Ministry of Agriculture of China, Yangzhou University, 48 Wenhui East Road, Yangzhou, Jiangsu, 225000, China.
Yuanyue TangJoint International Research Laboratory of Agriculture and Agri-product Safety, Yangzhou University, 48 Wenhui East Road, Yangzhou, Jiangsu, 225000, China.
Fangzhe RenJoint International Research Laboratory of Agriculture and Agri-product Safety, Yangzhou University, 48 Wenhui East Road, Yangzhou, Jiangsu, 225000, China.
Xinan JiaoJiangsu Key Lab of Zoonosis/Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, 48 Wenhui East Road, Yangzhou, Jiangsu, 225000, China.
Jinlin HuangJiangsu Key Lab of Zoonosis/Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, 48 Wenhui East Road, Yangzhou, Jiangsu, 225000, China. jinlin@yzu.edu.cn.

Funding

National Key Research and Development Program of China 2024YFC2310300National Natural Science Foundation of China 32473117The Young Scientists Fund of the National Natural Science Foundation of China 32202887Yangzhou Innovation Capability Enhancement Fund/ Program YZ2023245
6 · The paper itself

Abstract

Campylobacter jejuni (C. jejuni) is a significant foodborne pathogen. The rise of antibiotic-resistant strains has diminished the effectiveness of conventional treatments, highlighting the urgent need for safe and effective alternatives. In this study, a Bacillus safensis (B. safensis) strain (BS05) was isolated from goats and assessed for its probiotic properties and antagonistic activity against C. jejuni. BS05 formed rough colonies on agar, and scanning electron microscopy revealed predominantly short rod-shaped cells. The cell-free culture supernatant (CFS) of BS05 inhibited multiple C. jejuni strains of diverse sequence types. This inhibition was evidenced by reduced optical density (OD

Indexed as

Anti-Bacterial AgentsBacillusCampylobacter jejuniProbioticsAnimalsBacteriocinsCampylobacter InfectionsFemaleGoatsMiceMice, Inbred BALB CMicrobial Sensitivity TestsAnti-Bacterial AgentsBacteriocinsBacillus safensisBacteriocinsCampylobacter jejuniProbiotics

Identifiers

PMID41495638
PMCPMC12903218

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.